Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
HCC1143 | ABT-737 | 0.001 | Bcl2/XL | Misc | 1.0058 | -0.00733 |
PDX1258 | ABT-737 | 3.1623 | Bcl2/XL | Misc | 0.9143 | 0.04956 |
PDX1258 | ABT-737 | 1.0 | Bcl2/XL | Misc | 0.8902 | 0.03717 |
PDX1258 | ABT-737 | 10.0 | Bcl2/XL | Misc | 0.7580 | 0.08403 |
PDX1258 | ABT-737 | 0.31623 | Bcl2/XL | Misc | 0.9927 | 0.02272 |
PDX1258 | ABT-737 | 0.1 | Bcl2/XL | Misc | 1.0975 | 0.01407 |
MDA-MB-436 | ABT-737 | 0.031623 | Bcl2/XL | Misc | 0.9929 | 0.00058 |
PDX1258 | ABT-737 | 0.01 | Bcl2/XL | Misc | 1.0744 | -0.00310 |
PDX1258 | ABT-737 | 0.031623 | Bcl2/XL | Misc | 1.0684 | 0.01408 |
MDA-MB-436 | ABT-737 | 0.1 | Bcl2/XL | Misc | 1.0753 | 0.00211 |
PDX1258 | ABT-737 | 0.001 | Bcl2/XL | Misc | 1.0655 | -0.00693 |
MDA-MB-436 | ABT-737 | 0.31623 | Bcl2/XL | Misc | 1.0821 | 0.00380 |
PDX1258 | ABT-737 | 0.0031623 | Bcl2/XL | Misc | 1.0632 | 0.00164 |
HCC1395 | ABT-737 | 0.031623 | Bcl2/XL | Misc | 1.0777 | 0.00618 |
HCC1395 | ABT-737 | 0.1 | Bcl2/XL | Misc | 1.1223 | 0.00361 |
CAL-120 | ABT-737 | 0.031623 | Bcl2/XL | Misc | 1.0430 | 0.00331 |
CAL-120 | ABT-737 | 0.1 | Bcl2/XL | Misc | 1.0305 | 0.00949 |
HCC1395 | ABT-737 | 0.001 | Bcl2/XL | Misc | 1.0994 | -0.01093 |
MDA-MB-436 | ABT-737 | 0.001 | Bcl2/XL | Misc | 1.0291 | -0.00200 |
CAL-120 | ABT-737 | 0.001 | Bcl2/XL | Misc | 1.0022 | -0.00028 |
MDA-MB-436 | ABT-737 | 0.0031623 | Bcl2/XL | Misc | 1.0498 | -0.00265 |
HCC1395 | ABT-737 | 0.0031623 | Bcl2/XL | Misc | 1.0013 | 0.00867 |
CAL-120 | ABT-737 | 0.0031623 | Bcl2/XL | Misc | 1.0233 | -0.00607 |
MDA-MB-436 | ABT-737 | 0.01 | Bcl2/XL | Misc | 0.9682 | 0.00365 |
SK-BR-3 | ABT-737 | 1.0 | Bcl2/XL | Misc | 1.0019 | -0.00495 |