Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1395 Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0739 -0.00147
HCC1395 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0383 0.01125
SK-BR-3 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.7553 0.02927
HCC1395 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.7425 0.00797
PDX1258 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.3985 0.04601
HCC1395 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.4943 0.02516
MCF7 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.8212 0.01438
SK-BR-3 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.3560 0.09589
HCC1419 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.1535 -0.00296
HCC1419 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0749 -0.00409
MCF7 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9327 0.00677
HCC1419 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.7063 -0.00132
MCF7 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9728 0.00441
MCF7 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9829 0.00469
MCF7 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.2497 0.14778
PDX1328 Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0399 0.00359
MCF7 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.5403 0.03530
MCF7 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.6830 0.02591
MCF7 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.3934 0.07320
PDX1328 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0493 0.02225
PDX1328 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0885 0.01717
PDX1328 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.2222 -0.00663
PDX1328 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.3012 0.02812
CAL-120 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.5993 0.00381
CAL-120 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.7502 -0.00680