Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAL-51 Ceritinib
0.01
ALK
RTK
 0.9683 -0.00156
CAL-51 Ceritinib
0.031623
ALK
RTK
 0.9571 0.00298
HCC1419 Ceritinib
0.001
ALK
RTK
 0.9998 -0.00295
HCC1419 Ceritinib
0.0031623
ALK
RTK
 1.0655 -0.00043
HCC1419 Ceritinib
10.0
ALK
RTK
 -0.8670 0.78048
MDA-MB-361 Ceritinib
0.0031623
ALK
RTK
 0.9476 0.00361
MDA-MB-361 Ceritinib
10.0
ALK
RTK
 -0.9910 0.89628
MDA-MB-361 Ceritinib
0.001
ALK
RTK
 1.0347 0.00070
SUM149PT Ceritinib
0.0031623
ALK
RTK
 0.9871 0.00696
SUM149PT Ceritinib
0.01
ALK
RTK
 1.0285 0.00078
SK-BR-3 Ceritinib
0.1
ALK
RTK
 0.9793 -0.00117
MDA-MB-361 Ceritinib
3.1623
ALK
RTK
 -0.2646 0.19562
PDX1328 Ceritinib
10.0
ALK
RTK
 -0.9426 0.68787
HCC70 Ceritinib
10.0
ALK
RTK
 -0.8808 0.51303
HCC70 Ceritinib
3.1623
ALK
RTK
 0.5169 0.11437
HCC70 Ceritinib
0.001
ALK
RTK
 1.4221 0.00355
SK-BR-3 Ceritinib
0.031623
ALK
RTK
 1.0386 -0.00756
MCF7 Ceritinib
0.031623
ALK
RTK
 0.9756 0.00574
MDA-MB-361 Ceritinib
1.0
ALK
RTK
 0.0060 0.10589
MCF7 Ceritinib
0.1
ALK
RTK
 0.8293 0.01447
SK-BR-3 Ceritinib
0.001
ALK
RTK
 1.0870 0.01087
BT-20 Ceritinib
1.0
ALK
RTK
 0.7206 0.03294
HCC70 Ceritinib
0.1
ALK
RTK
 1.1214 0.00001
BT-20 Ceritinib
0.1
ALK
RTK
 1.0073 0.00247
MCF7 Ceritinib
0.31623
ALK
RTK
 0.5120 0.03603