Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
PDX1258 Ceritinib
0.0031623
ALK
RTK
 1.0672 0.00314
Hs 578T Ceritinib
10.0
ALK
RTK
 -0.4356 0.67418
PDX1258 Ceritinib
0.01
ALK
RTK
 1.1078 -0.00605
PDX1258 Ceritinib
10.0
ALK
RTK
 -0.6841 0.60042
HCC1500 Ceritinib
0.01
ALK
RTK
 1.0163 0.01634
HCC1500 Ceritinib
0.031623
ALK
RTK
 1.0825 0.00012
Hs 578T Ceritinib
0.1
ALK
RTK
 0.9622 0.01408
BT-20 Ceritinib
0.0031623
ALK
RTK
 1.0478 -0.00217
Hs 578T Ceritinib
0.31623
ALK
RTK
 0.8074 0.04877
MDA-MB-361 Ceritinib
3.1623
ALK
RTK
 -0.2646 0.19562
MCF 10A Ceritinib
3.1623
ALK
RTK
 0.5414 0.01676
MDA-MB-361 Ceritinib
10.0
ALK
RTK
 -0.9910 0.89628
MCF 10A Ceritinib
10.0
ALK
RTK
 -0.3186 0.46177
HCC38 Ceritinib
0.0031623
ALK
RTK
 1.0734 0.01015
HCC38 Ceritinib
0.01
ALK
RTK
 1.0960 -0.00029
HCC38 Ceritinib
0.31623
ALK
RTK
 0.9475 0.00674
MCF7 Ceritinib
1.0
ALK
RTK
 0.0289 0.16654
HCC38 Ceritinib
3.1623
ALK
RTK
 0.0064 0.23382
HCC38 Ceritinib
1.0
ALK
RTK
 0.8629 0.02536
BT-20 Ceritinib
0.01
ALK
RTK
 1.0693 -0.00162
HCC1500 Ceritinib
0.001
ALK
RTK
 1.1491 0.00774
BT-20 Ceritinib
0.001
ALK
RTK
 1.0413 -0.00151
BT-20 Ceritinib
0.031623
ALK
RTK
 1.0677 -0.00061
PDX1258 Ceritinib
0.001
ALK
RTK
 1.1222 -0.00184
HCC1500 Ceritinib
0.0031623
ALK
RTK
 1.1700 0.00728