Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAL-51 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9095 0.00961
CAL-51 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.6909 0.03483
CAL-51 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.6210 0.03901
MCF7 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9728 0.00441
SK-BR-3 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0404 0.00786
SK-BR-3 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9410 0.00816
SK-BR-3 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.6485 0.02750
SK-BR-3 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.7553 0.02927
Hs 578T Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4423 0.04240
MDA-MB-134-VI Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.2763 0.01177
MDA-MB-134-VI Ipatasertib
0.01
AKT
PI3K/mTOR
 1.2946 -0.00070
MCF7 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.3934 0.07320
MCF7 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9327 0.00677
MDA-MB-157 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9336 0.01107
HCC1395 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.3690 0.03281
HCC1419 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0076 0.00354
HCC1419 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.1535 -0.00296
HCC1419 Ipatasertib
0.1
AKT
PI3K/mTOR
 1.0291 0.00075
HCC1419 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.8917 -0.00505
MDA-MB-134-VI Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4925 0.02851
MCF7 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.5403 0.03530
MDA-MB-134-VI Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.8501 0.01167
MDA-MB-134-VI Ipatasertib
1.0
AKT
PI3K/mTOR
 1.0087 0.00967
SUM1315MO2 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9240 0.01094
SUM1315MO2 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9968 0.00116