Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
T47D Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0666 0.00107
T47D Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9092 0.00291
T47D Ipatasertib
0.1
AKT
PI3K/mTOR
 0.5806 0.00422
T47D Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.3286 0.01648
MCF 10A Ipatasertib
1.0
AKT
PI3K/mTOR
 0.9214 -0.00401
MCF7 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.5403 0.03530
BT-549 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.8348 0.00416
BT-549 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9311 0.00802
BT-549 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.6422 0.02457
BT-549 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.7136 0.00345
BT-549 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4956 0.02987
MDA-MB-134-VI Ipatasertib
0.1
AKT
PI3K/mTOR
 1.0768 0.00558
PDX1258 Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0745 -0.00113
MDA-MB-436 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.8217 0.00883
MDA-MB-436 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.6111 0.04354
MDA-MB-453 Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0560 0.01612
MDA-MB-453 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.1257 0.02296
MDA-MB-453 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9311 0.02532
MDA-MB-453 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.2590 0.12602
MDA-MB-453 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.0389 0.18071
PDX1258 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0340 0.00014
PDX1258 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.6900 0.01459
MCF 10A Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0078 0.00047
CAMA-1 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.7817 0.00048
CAMA-1 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.8955 -0.00218