Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 Olaparib
0.0031623
PARP
Misc
 1.0401 -0.00692
HCC1806 A-1210477
3.1623
Mcl-1
Misc
 1.0029 -0.00692
SUM159PT Pictilisib
0.31623
pan PI3K
PI3K/mTOR
 0.8144 -0.00692
HCC1428 Cisplatin
0.31623
Chemo
Chemotherapy
 0.7479 -0.00691
SK-BR-3 A-1210477
3.1623
Mcl-1
Misc
 0.9958 -0.00690
HCC1937 Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.9367 -0.00690
HCC1428 Bleomycin
0.01
Radiation
Misc
 0.8377 -0.00689
HCC1954 Ceritinib
0.0031623
ALK
RTK
 1.1155 -0.00688
CAMA-1 Dasatinib
1.0
BCR/ABL
MAPK/nRTK
 0.7975 -0.00687
MDA-MB-436 Etoposide
0.031667
Topo II
Chemotherapy
 0.9635 -0.00687
HCC38 Buparlisib
0.031623
pan PI3K
PI3K/mTOR
 1.0006 -0.00684
HCC1500 Alpelisib
0.01
PI3Ka
PI3K/mTOR
 1.1895 -0.00683
HCC1806 Cisplatin
0.1
Chemo
Chemotherapy
 0.9733 -0.00682
MDA-MB-231 Olaparib
1.0
PARP
Misc
 0.9368 -0.00682
CAMA-1 Palbociclib
0.031623
CDK4/6
Cell cycle
 0.6754 -0.00682
CAL-120 TGX221
10.0
PI3Kb
PI3K/mTOR
 1.0198 -0.00680
CAL-120 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.7502 -0.00680
CAMA-1 Dasatinib
10.0
BCR/ABL
MAPK/nRTK
 0.6790 -0.00678
CAMA-1 Cediranib
3.1623
VEGFR/cKIT
RTK
 0.8129 -0.00677
MDA-MB-453 Dinaciclib
0.0031623
pan CDK
Cell cycle
 1.0101 -0.00676
HCC70 Dinaciclib
0.0031623
pan CDK
Cell cycle
 1.2444 -0.00676
PDXHCI002 Alpelisib
0.001
PI3Ka
PI3K/mTOR
 0.9855 -0.00673
PDX1328 Bleomycin
1.0
Radiation
Misc
 0.7863 -0.00672
SUM149PT Abemaciclib
0.0031623
CDK4/6
Cell cycle
 1.0233 -0.00672
BT-549 Vorinostat
0.1
HDAC
Misc
 0.9070 -0.00670