Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HME1 Doxorubicin
0.031623
Chemo
Chemotherapy
 0.0107 0.18994
HME1 Doxorubicin
0.1
Chemo
Chemotherapy
 -0.0999 0.31736
HME1 Doxorubicin
0.31623
Chemo
Chemotherapy
 -0.2454 0.47624
HME1 Doxorubicin
1.0
Chemo
Chemotherapy
 -0.2974 0.59384
HME1 Doxorubicin
3.1623
Chemo
Chemotherapy
 -0.3985 0.73487
HME1 Taxol
0.0001
Chemo
Chemotherapy
 0.9387 0.02046
HME1 Taxol
0.00031623
Chemo
Chemotherapy
 1.0789 -0.00273
HME1 Taxol
0.001
Chemo
Chemotherapy
 0.9353 0.03041
HME1 Taxol
0.0031623
Chemo
Chemotherapy
 0.4376 0.19940
HME1 Taxol
0.01
Chemo
Chemotherapy
 0.0903 0.34756
HME1 Taxol
0.031623
Chemo
Chemotherapy
 -0.0253 0.34280
HME1 Taxol
0.1
Chemo
Chemotherapy
 -0.1170 0.39486
HME1 Taxol
0.31623
Chemo
Chemotherapy
 -0.1636 0.39494
HME1 Taxol
1.0
Chemo
Chemotherapy
 -0.2241 0.43304
HME1 Topotecan
0.0010833
Topo I
Chemotherapy
 0.9541 -0.00341
HME1 Topotecan
0.0033333
Topo I
Chemotherapy
 0.7745 0.00175
HME1 Topotecan
0.01
Topo I
Chemotherapy
 0.3567 0.12123
HME1 Topotecan
0.031667
Topo I
Chemotherapy
 -0.0165 0.25485
HME1 Topotecan
0.1
Topo I
Chemotherapy
 0.0142 0.22504
HME1 Topotecan
0.31623
Topo I
Chemotherapy
 -0.0387 0.28056
HME1 Topotecan
1.0
Topo I
Chemotherapy
 -0.0957 0.28540
HME1 Topotecan
3.1623
Topo I
Chemotherapy
 -0.2456 0.47934
HME1 Topotecan
10.0
Topo I
Chemotherapy
 -0.3399 0.63621
HME1 Etoposide
0.0010833
Topo II
Chemotherapy
 1.0092 -0.00139
HME1 Etoposide
0.0033333
Topo II
Chemotherapy
 0.9838 0.00190