Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAL-120 Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.9547 0.00475
CAL-120 Alpelisib
0.01
PI3Ka
PI3K/mTOR
 1.0233 0.00352
CAL-120 Alpelisib
0.031623
PI3Ka
PI3K/mTOR
 0.9692 -0.00272
CAL-120 Alpelisib
0.1
PI3Ka
PI3K/mTOR
 0.9133 -0.00153
CAL-120 Alpelisib
0.31623
PI3Ka
PI3K/mTOR
 0.9227 -0.00661
CAL-120 Alpelisib
1.0
PI3Ka
PI3K/mTOR
 0.8571 -0.00418
CAL-120 Alpelisib
3.1623
PI3Ka
PI3K/mTOR
 0.8251 -0.00750
CAL-120 Alpelisib
10.0
PI3Ka
PI3K/mTOR
 0.6075 -0.00392
CAL-120 Taselisib
0.001
PI3Ka, g, d
PI3K/mTOR
 0.9485 -0.00115
CAL-120 Taselisib
0.0031623
PI3Ka, g, d
PI3K/mTOR
 0.8898 -0.00202
CAL-120 Taselisib
0.01
PI3Ka, g, d
PI3K/mTOR
 0.9613 -0.00471
CAL-120 Taselisib
0.031623
PI3Ka, g, d
PI3K/mTOR
 0.8922 0.00080
CAL-120 Taselisib
0.1
PI3Ka, g, d
PI3K/mTOR
 0.8244 -0.00079
CAL-120 Taselisib
0.31623
PI3Ka, g, d
PI3K/mTOR
 0.7760 -0.00097
CAL-120 Taselisib
1.0
PI3Ka, g, d
PI3K/mTOR
 0.7089 0.00151
CAL-120 Taselisib
3.1623
PI3Ka, g, d
PI3K/mTOR
 0.5180 0.01952
CAL-120 Taselisib
10.0
PI3Ka, g, d
PI3K/mTOR
 0.1514 0.10375
CAL-120 TGX221
0.001
PI3Kb
PI3K/mTOR
 0.9961 -0.00346
CAL-120 TGX221
0.0031623
PI3Kb
PI3K/mTOR
 0.9779 -0.00553
CAL-120 TGX221
0.01
PI3Kb
PI3K/mTOR
 1.0367 -0.00756
CAL-120 TGX221
0.031623
PI3Kb
PI3K/mTOR
 1.0117 -0.00323
CAL-120 TGX221
0.1
PI3Kb
PI3K/mTOR
 0.9832 -0.00553
CAL-120 TGX221
0.31623
PI3Kb
PI3K/mTOR
 1.0346 -0.00999
CAL-120 TGX221
1.0
PI3Kb
PI3K/mTOR
 1.0417 -0.00517
CAL-120 TGX221
3.1623
PI3Kb
PI3K/mTOR
 1.0407 -0.00622