Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 Neratinib
0.1
EGFR/HER2
RTK
 0.7682 0.05014
HCC1806 Neratinib
0.31623
EGFR/HER2
RTK
 0.7026 0.06151
HCC1806 Neratinib
1.0
EGFR/HER2
RTK
 0.5513 0.07881
HCC1806 Neratinib
3.1623
EGFR/HER2
RTK
 -0.0883 0.43583
HCC1806 Tivantinib
0.001
MET
RTK
 1.0293 0.00356
HCC1806 Tivantinib
0.0031623
MET
RTK
 0.9997 0.00401
HCC1806 Tivantinib
0.01
MET
RTK
 1.0496 -0.00152
HCC1806 Tivantinib
0.031623
MET
RTK
 1.0186 0.00130
HCC1806 Tivantinib
0.1
MET
RTK
 0.9630 0.00521
HCC1806 Tivantinib
0.31623
MET
RTK
 0.3568 0.15622
HCC1806 Tivantinib
1.0
MET
RTK
 -0.1778 0.49866
HCC1806 Tivantinib
3.1623
MET
RTK
 -0.1869 0.48586
HCC1806 Tivantinib
10.0
MET
RTK
 -0.2185 0.47523
HCC1806 Cediranib
0.001
VEGFR/cKIT
RTK
 0.9923 0.00046
HCC1806 Cediranib
0.0031623
VEGFR/cKIT
RTK
 1.0810 -0.01058
HCC1806 Cediranib
0.01
VEGFR/cKIT
RTK
 1.0401 0.00080
HCC1806 Cediranib
0.031623
VEGFR/cKIT
RTK
 0.9721 0.00716
HCC1806 Cediranib
0.1
VEGFR/cKIT
RTK
 0.9983 0.00263
HCC1806 Cediranib
0.31623
VEGFR/cKIT
RTK
 0.9459 0.01658
HCC1806 Cediranib
1.0
VEGFR/cKIT
RTK
 1.0383 0.00958
HCC1806 Cediranib
3.1623
VEGFR/cKIT
RTK
 0.8954 0.02498
HCC1806 Cediranib
10.0
VEGFR/cKIT
RTK
 0.0954 0.27518
HCC1806 Cabozantinib
0.001
VEGFR2/MET
RTK
 1.0034 0.00114
HCC1806 Cabozantinib
0.0031623
VEGFR2/MET
RTK
 0.9662 0.00320
HCC1806 Cabozantinib
0.01
VEGFR2/MET
RTK
 1.0074 0.00021