LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. - Dataset (ID:20316)
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| Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 72 | Inf | Inf | 0.8047 | 0.8047 | 0.0000 | 0.2441 |
| MCF 10A-H2B-mCherry | Alpelisib | 48 | Inf | Inf | 0.7368 | 0.7368 | 0.0000 | 0.2612 |
| MCF 10A-H2B-mCherry | Trametinib | 84 | 6.7955 | 0.0263 | 0.5589 | 0.3962 | 0.2830 | 0.2816 |
| MCF 10A-H2B-mCherry | Alpelisib | 36 | Inf | Inf | 0.7055 | 0.7055 | 0.0000 | 0.2829 |
| MCF 10A-H2B-mCherry | Trametinib | 72 | Inf | 0.0048 | 0.5610 | 0.5286 | 0.5137 | 0.2868 |
| MCF 10A-H2B-mCherry | Alpelisib | 84 | Inf | Inf | 0.7374 | 0.7374 | 0.0000 | 0.3018 |
| MCF 10A-H2B-mCherry | Trametinib | 24 | Inf | Inf | 0.7135 | 0.7135 | 0.0000 | 0.3120 |
| MCF 10A-H2B-mCherry | Etoposide | 24 | Inf | Inf | 0.2285 | 0.2285 | 0.0000 | 0.3229 |
| MCF 10A-H2B-mCherry | Palbociclib | 72 | Inf | Inf | 0.4218 | 0.4218 | 0.0000 | 0.3265 |
| MCF 10A-H2B-mCherry | Alpelisib | 24 | Inf | Inf | 0.6050 | 0.6050 | 0.0000 | 0.3309 |
| MCF 10A-H2B-mCherry | Palbociclib | 84 | Inf | Inf | 0.3876 | 0.3876 | 0.0000 | 0.3349 |
| MCF 10A-H2B-mCherry | Trametinib | 36 | Inf | Inf | 0.6568 | 0.6568 | 0.0000 | 0.3354 |
| MCF 10A-H2B-mCherry | Trametinib | 48 | Inf | 0.0003 | 0.5877 | 0.5701 | 0.3964 | 0.3405 |
| MCF 10A-H2B-mCherry | Etoposide | 36 | 1.7174 | 246.1221 | 0.1871 | -1.0000 | 0.2213 | 0.3418 |
| MCF 10A-H2B-mCherry | Palbociclib | 48 | Inf | Inf | 0.3655 | 0.3655 | 0.0000 | 0.3443 |
| MCF 10A-H2B-mCherry | Etoposide | 48 | 1.0407 | 79.7605 | 0.1715 | -1.0000 | 0.2532 | 0.3575 |
| MCF 10A-H2B-mCherry | Palbociclib | 36 | Inf | Inf | 0.3397 | 0.3397 | 0.0000 | 0.3606 |
| MCF 10A-H2B-mCherry | Vorinostat | 48 | 1.111 | 15.0584 | 0.1025 | -1.0000 | 0.4215 | 0.3662 |
| MCF 10A-H2B-mCherry | Vorinostat | 72 | 1.435 | 21.5194 | 0.1227 | -1.0000 | 0.4057 | 0.3663 |
| MCF 10A-H2B-mCherry | Vorinostat | 36 | 1.0852 | 20.5497 | 0.1559 | -1.0000 | 0.3735 | 0.3694 |
| MCF 10A-H2B-mCherry | Neratinib | 72 | 0.2915 | 6.6939 | 0.0859 | -1.0000 | 0.3505 | 0.3727 |
| MCF 10A-H2B-mCherry | Vorinostat | 24 | 1.2461 | 204.8226 | 0.2649 | -1.0000 | 0.2153 | 0.3813 |
| MCF 10A-H2B-mCherry | Palbociclib | 24 | Inf | Inf | 0.3926 | 0.3926 | 0.0000 | 0.3827 |
| MCF 10A-H2B-mCherry | Neratinib | 24 | 0.3492 | 0.0073 | 0.4236 | 0.3755 | 0.3591 | 0.3870 |
| MCF 10A-H2B-mCherry | Dasatinib | 72 | Inf | Inf | 0.2033 | 0.2033 | 0.0000 | 0.3884 |