LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. - Dataset (ID:20316)

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Cell Small Molecule Time Point (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Taxol 84
0.0003
0.0008
-0.2773 -0.3429 0.6241 0.8762
MCF 10A-H2B-mCherry Taxol 12
0.0005
0.0007
0.2488 -0.0238 0.1003 0.5527
MCF 10A-H2B-mCherry Taxol 72
0.0005
0.0011
-0.2898 -0.3494 0.6605 0.8468
MCF 10A-H2B-mCherry Taxol 48
0.0009
0.0023
-0.2904 -0.4105 0.6256 0.7874
MCF 10A-H2B-mCherry Taxol 36
0.0012
0.004
-0.2810 -0.4927 0.5556 0.7513
MCF 10A-H2B-mCherry Taxol 24
0.0018
0.0505
-0.2179 -1.0000 0.3299 0.6617
MCF 10A-H2B-mCherry Neratinib 36
0.1336
0.0994
0.2934 0.0455 0.3225 0.4123
MCF 10A-H2B-mCherry Etoposide 84
0.1739
59.2726
0.1678 -1.0000 0.1884 0.4947
MCF 10A-H2B-mCherry Neratinib 48
0.2009
11.344
0.1627 -1.0000 0.2724 0.3954
MCF 10A-H2B-mCherry Neratinib 84
0.2528
9.4484
0.0272 -1.0000 0.3034 0.3990
MCF 10A-H2B-mCherry Neratinib 72
0.2915
6.6939
0.0859 -1.0000 0.3505 0.3727
MCF 10A-H2B-mCherry Neratinib 24
0.3492
0.0073
0.4236 0.3755 0.3591 0.3870
MCF 10A-H2B-mCherry Etoposide 72
0.4072
92.5315
0.1613 -1.0000 0.2025 0.4334
MCF 10A-H2B-mCherry Etoposide 48
1.0407
79.7605
0.1715 -1.0000 0.2532 0.3575
MCF 10A-H2B-mCherry Vorinostat 36
1.0852
20.5497
0.1559 -1.0000 0.3735 0.3694
MCF 10A-H2B-mCherry Vorinostat 48
1.111
15.0584
0.1025 -1.0000 0.4215 0.3662
MCF 10A-H2B-mCherry Vorinostat 84
1.1734
54.8915
0.1209 -1.0000 0.2857 0.4069
MCF 10A-H2B-mCherry Vorinostat 24
1.2461
204.8226
0.2649 -1.0000 0.2153 0.3813
MCF 10A-H2B-mCherry Vorinostat 72
1.435
21.5194
0.1227 -1.0000 0.4057 0.3663
MCF 10A-H2B-mCherry Etoposide 36
1.7174
246.1221
0.1871 -1.0000 0.2213 0.3418
MCF 10A-H2B-mCherry Trametinib 84
6.7955
0.0263
0.5589 0.3962 0.2830 0.2816
MCF 10A-H2B-mCherry Trametinib 12
Inf
Inf
0.5691 0.5691 0.0000 0.4204
MCF 10A-H2B-mCherry Trametinib 24
Inf
Inf
0.7135 0.7135 0.0000 0.3120
MCF 10A-H2B-mCherry Trametinib 36
Inf
Inf
0.6568 0.6568 0.0000 0.3354
MCF 10A-H2B-mCherry Trametinib 48
Inf
0.0003
0.5877 0.5701 0.3964 0.3405
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