LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. - Dataset (ID:20316)
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Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Etoposide | 12 | Inf | Inf | 0.3263 | 0.3263 | 0.0000 | 0.4338 |
MCF 10A-H2B-mCherry | Alpelisib | 24 | Inf | Inf | 0.6050 | 0.6050 | 0.0000 | 0.3309 |
MCF 10A-H2B-mCherry | Alpelisib | 36 | Inf | Inf | 0.7055 | 0.7055 | 0.0000 | 0.2829 |
MCF 10A-H2B-mCherry | Alpelisib | 48 | Inf | Inf | 0.7368 | 0.7368 | 0.0000 | 0.2612 |
MCF 10A-H2B-mCherry | Alpelisib | 72 | Inf | Inf | 0.8047 | 0.8047 | 0.0000 | 0.2441 |
MCF 10A-H2B-mCherry | Alpelisib | 84 | Inf | Inf | 0.7374 | 0.7374 | 0.0000 | 0.3018 |
MCF 10A-H2B-mCherry | Dasatinib | 12 | Inf | Inf | 0.4761 | 0.4761 | 0.0000 | 0.4903 |
MCF 10A-H2B-mCherry | Dasatinib | 24 | Inf | Inf | 0.3885 | 0.3885 | 0.0000 | 0.4429 |
MCF 10A-H2B-mCherry | Dasatinib | 36 | Inf | Inf | 0.3554 | 0.3554 | 0.0000 | 0.4191 |
MCF 10A-H2B-mCherry | Dasatinib | 48 | Inf | Inf | 0.3357 | 0.3357 | 0.0000 | 0.3927 |
MCF 10A-H2B-mCherry | Dasatinib | 72 | Inf | Inf | 0.2033 | 0.2033 | 0.0000 | 0.3884 |
MCF 10A-H2B-mCherry | Dasatinib | 84 | Inf | Inf | 0.1459 | 0.1459 | 0.0000 | 0.4301 |
MCF 10A-H2B-mCherry | Alpelisib | 12 | Inf | Inf | 0.5346 | 0.5346 | 0.0000 | 0.4462 |
MCF 10A-H2B-mCherry | Etoposide | 24 | Inf | Inf | 0.2285 | 0.2285 | 0.0000 | 0.3229 |
MCF 10A-H2B-mCherry | Neratinib | 12 | Inf | Inf | 0.4696 | 0.4696 | 0.0000 | 0.4345 |
MCF 10A-H2B-mCherry | Palbociclib | 12 | Inf | Inf | 0.4654 | 0.4654 | 0.0000 | 0.4378 |
MCF 10A-H2B-mCherry | Palbociclib | 24 | Inf | Inf | 0.3926 | 0.3926 | 0.0000 | 0.3827 |
MCF 10A-H2B-mCherry | Palbociclib | 36 | Inf | Inf | 0.3397 | 0.3397 | 0.0000 | 0.3606 |
MCF 10A-H2B-mCherry | Palbociclib | 48 | Inf | Inf | 0.3655 | 0.3655 | 0.0000 | 0.3443 |
MCF 10A-H2B-mCherry | Palbociclib | 72 | Inf | Inf | 0.4218 | 0.4218 | 0.0000 | 0.3265 |
MCF 10A-H2B-mCherry | Palbociclib | 84 | Inf | Inf | 0.3876 | 0.3876 | 0.0000 | 0.3349 |
MCF 10A-H2B-mCherry | Trametinib | 12 | Inf | Inf | 0.5691 | 0.5691 | 0.0000 | 0.4204 |
MCF 10A-H2B-mCherry | Trametinib | 24 | Inf | Inf | 0.7135 | 0.7135 | 0.0000 | 0.3120 |
MCF 10A-H2B-mCherry | Trametinib | 36 | Inf | Inf | 0.6568 | 0.6568 | 0.0000 | 0.3354 |
MCF 10A-H2B-mCherry | Vorinostat | 12 | Inf | Inf | 0.4594 | 0.4594 | 0.0000 | 0.4495 |