LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 7 of 15: End-point dose-response metrics for biological replicate 1. - Dataset (ID:20315)
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| Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 36 | 0.0036 | 0.0060 | -0.6322 | -0.5696 | 1.4542 | 0.6936 |
| MCF 10A-H2B-mCherry | Taxol | 49 | 0.0026 | 0.0045 | -0.5907 | -0.5232 | 1.3137 | 0.7187 |
| MCF 10A-H2B-mCherry | Taxol | 25 | 0.006 | 0.0088 | -0.5788 | -0.5111 | 1.8512 | 0.6091 |
| MCF 10A-H2B-mCherry | Taxol | 60 | 0.0024 | 0.0038 | -0.5376 | -0.4605 | 1.4197 | 0.7151 |
| MCF 10A-H2B-mCherry | Taxol | 74 | 0.0023 | 0.0034 | -0.4930 | -0.4115 | 1.5424 | 0.7101 |
| MCF 10A-H2B-mCherry | Taxol | 85 | 0.0023 | 0.0033 | -0.4886 | -0.4051 | 1.6490 | 0.7131 |
| MCF 10A-H2B-mCherry | Taxol | 14 | 0.0086 | 0.0094 | -0.3292 | -0.2527 | 5.0000 | 0.4921 |
| MCF 10A-H2B-mCherry | Vorinostat | 60 | 1.0712 | 1.2024 | -0.0684 | -0.1062 | 1.6672 | 0.3109 |
| MCF 10A-H2B-mCherry | Vorinostat | 49 | 0.9385 | 1.0915 | -0.0683 | -0.1220 | 1.4457 | 0.3318 |
| MCF 10A-H2B-mCherry | Vorinostat | 74 | 1.2172 | 1.3203 | -0.0640 | -0.0849 | 1.9279 | 0.2897 |
| MCF 10A-H2B-mCherry | Vorinostat | 85 | 1.307 | 1.3899 | -0.0587 | -0.0691 | 2.1072 | 0.2776 |
| MCF 10A-H2B-mCherry | Vorinostat | 36 | 0.8145 | 0.9868 | -0.0499 | -0.1303 | 1.2067 | 0.3492 |
| MCF 10A-H2B-mCherry | Vorinostat | 25 | 0.7805 | 1.0475 | -0.0221 | -0.1584 | 0.9356 | 0.3490 |
| MCF 10A-H2B-mCherry | Dasatinib | 85 | 1.1883 | 11.0713 | -0.0204 | -1.0000 | 0.4922 | 0.2947 |
| MCF 10A-H2B-mCherry | Neratinib | 85 | 0.2047 | 0.2231 | -0.0133 | -0.0516 | 1.1390 | 0.3213 |
| MCF 10A-H2B-mCherry | Etoposide | 85 | 0.4487 | 0.4530 | 0.0008 | -0.0071 | 1.4840 | 0.3508 |
| MCF 10A-H2B-mCherry | Etoposide | 74 | 0.4441 | 0.4511 | 0.0118 | -0.0110 | 1.3847 | 0.3505 |
| MCF 10A-H2B-mCherry | Etoposide | 49 | 0.4668 | 0.4781 | 0.0158 | -0.0157 | 1.2947 | 0.3416 |
| MCF 10A-H2B-mCherry | Dasatinib | 74 | 1.127 | 11.8661 | 0.0188 | -1.0000 | 0.4667 | 0.2978 |
| MCF 10A-H2B-mCherry | Etoposide | 60 | 0.4484 | 0.4561 | 0.0206 | -0.0114 | 1.3240 | 0.3465 |
| MCF 10A-H2B-mCherry | Neratinib | 74 | 0.1646 | 0.1622 | 0.0239 | 0.0094 | 1.2986 | 0.3339 |
| MCF 10A-H2B-mCherry | Etoposide | 36 | 0.542 | 0.5522 | 0.0298 | -0.0120 | 1.2808 | 0.3248 |
| MCF 10A-H2B-mCherry | Etoposide | 25 | 0.6735 | 0.6909 | 0.0421 | -0.0166 | 1.2824 | 0.3073 |
| MCF 10A-H2B-mCherry | Dasatinib | 60 | 0.9634 | 4.3329 | 0.0547 | -0.5493 | 0.4931 | 0.3012 |
| MCF 10A-H2B-mCherry | Neratinib | 60 | 0.1262 | 0.1133 | 0.0711 | 0.0699 | 1.4052 | 0.3452 |