LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 7 of 15: End-point dose-response metrics for biological replicate 1. - Dataset (ID:20315)
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| Cell | Small Molecule | Time Point (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 85 | 1.1883 | 11.0713 | -0.0204 | -1.0000 | 0.4922 | 0.2947 |
| MCF 10A-H2B-mCherry | Dasatinib | 74 | 1.127 | 11.8661 | 0.0188 | -1.0000 | 0.4667 | 0.2978 |
| MCF 10A-H2B-mCherry | Alpelisib | 74 | 31.5401 | 177.9526 | 0.7039 | -1.0000 | 0.6349 | 0.0560 |
| MCF 10A-H2B-mCherry | Alpelisib | 85 | 38.4875 | 239.7081 | 0.7147 | -0.9999 | 0.6006 | 0.0545 |
| MCF 10A-H2B-mCherry | Alpelisib | 49 | 24.7897 | 113.5315 | 0.6824 | -0.9254 | 0.6885 | 0.0557 |
| MCF 10A-H2B-mCherry | Alpelisib | 60 | 26.0457 | 109.4817 | 0.6959 | -0.8810 | 0.7075 | 0.0512 |
| MCF 10A-H2B-mCherry | Dasatinib | 14 | 7.4345 | 45.0580 | 0.4382 | -0.6543 | 0.4643 | 0.1430 |
| MCF 10A-H2B-mCherry | Taxol | 36 | 0.0036 | 0.0060 | -0.6322 | -0.5696 | 1.4542 | 0.6936 |
| MCF 10A-H2B-mCherry | Dasatinib | 60 | 0.9634 | 4.3329 | 0.0547 | -0.5493 | 0.4931 | 0.3012 |
| MCF 10A-H2B-mCherry | Taxol | 49 | 0.0026 | 0.0045 | -0.5907 | -0.5232 | 1.3137 | 0.7187 |
| MCF 10A-H2B-mCherry | Taxol | 25 | 0.006 | 0.0088 | -0.5788 | -0.5111 | 1.8512 | 0.6091 |
| MCF 10A-H2B-mCherry | Taxol | 60 | 0.0024 | 0.0038 | -0.5376 | -0.4605 | 1.4197 | 0.7151 |
| MCF 10A-H2B-mCherry | Taxol | 74 | 0.0023 | 0.0034 | -0.4930 | -0.4115 | 1.5424 | 0.7101 |
| MCF 10A-H2B-mCherry | Taxol | 85 | 0.0023 | 0.0033 | -0.4886 | -0.4051 | 1.6490 | 0.7131 |
| MCF 10A-H2B-mCherry | Taxol | 14 | 0.0086 | 0.0094 | -0.3292 | -0.2527 | 5.0000 | 0.4921 |
| MCF 10A-H2B-mCherry | Vorinostat | 25 | 0.7805 | 1.0475 | -0.0221 | -0.1584 | 0.9356 | 0.3490 |
| MCF 10A-H2B-mCherry | Vorinostat | 36 | 0.8145 | 0.9868 | -0.0499 | -0.1303 | 1.2067 | 0.3492 |
| MCF 10A-H2B-mCherry | Vorinostat | 49 | 0.9385 | 1.0915 | -0.0683 | -0.1220 | 1.4457 | 0.3318 |
| MCF 10A-H2B-mCherry | Dasatinib | 49 | 0.7746 | 1.1082 | 0.0954 | -0.1144 | 0.5751 | 0.3048 |
| MCF 10A-H2B-mCherry | Vorinostat | 60 | 1.0712 | 1.2024 | -0.0684 | -0.1062 | 1.6672 | 0.3109 |
| MCF 10A-H2B-mCherry | Vorinostat | 74 | 1.2172 | 1.3203 | -0.0640 | -0.0849 | 1.9279 | 0.2897 |
| MCF 10A-H2B-mCherry | Vorinostat | 85 | 1.307 | 1.3899 | -0.0587 | -0.0691 | 2.1072 | 0.2776 |
| MCF 10A-H2B-mCherry | Alpelisib | 36 | 29.4183 | 34.2284 | 0.6713 | -0.0572 | 0.7153 | 0.0579 |
| MCF 10A-H2B-mCherry | Neratinib | 85 | 0.2047 | 0.2231 | -0.0133 | -0.0516 | 1.1390 | 0.3213 |
| MCF 10A-H2B-mCherry | Etoposide | 25 | 0.6735 | 0.6909 | 0.0421 | -0.0166 | 1.2824 | 0.3073 |