LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 50.00 | 19.50 | 4539 | 4744 | 0.9495 | 0.8420 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 51.90 | 19.50 | 4849 | 4974 | 0.9623 | 0.8454 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 53.90 | 19.50 | 5267 | 5154 | 1.0037 | 0.8565 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 55.90 | 19.50 | 5711 | 5348 | 1.0425 | 0.8600 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 57.80 | 19.50 | 6143 | 5483 | 1.0901 | 0.8721 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 59.80 | 19.50 | 6566 | 5578 | 1.1444 | 0.8751 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 62.80 | 19.50 | 6876 | 5586 | 1.1979 | 0.8873 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 64.70 | 19.50 | 7143 | 5643 | 1.2316 | 0.8951 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 66.70 | 19.50 | 7364 | 5728 | 1.2538 | 0.8938 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 68.70 | 19.50 | 7612 | 5743 | 1.2941 | 0.9088 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 70.70 | 19.50 | 7745 | 5784 | 1.3130 | 0.8827 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 72.60 | 19.50 | 7923 | 5854 | 1.3339 | 0.9113 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 74.60 | 19.50 | 8027 | 5927 | 1.3364 | 0.9155 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 76.60 | 19.50 | 7974 | 5898 | 1.3400 | 0.9105 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 78.50 | 19.50 | 7943 | 5949 | 1.3243 | 0.9108 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 80.50 | 19.50 | 7790 | 6018 | 1.2861 | 0.9003 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 82.50 | 19.50 | 7473 | 6031 | 1.2338 | 0.8836 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 84.40 | 19.50 | 7366 | 6038 | 1.2169 | 0.8728 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 86.40 | 19.50 | 7265 | 6081 | 1.1930 | 0.8337 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 88.40 | 19.50 | 7139 | 6064 | 1.1770 | 0.8440 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 90.40 | 19.50 | 7165 | 6097 | 1.1754 | 0.8310 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 92.30 | 19.50 | 7043 | 6153 | 1.1450 | 0.7830 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 94.30 | 19.50 | 6969 | 6154 | 1.1328 | 0.6914 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 2.70 | 19.50 | 186 | 163 | 1.1117 | 0.4786 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 4.60 | 19.50 | 266 | 295 | 0.8934 | 0.3925 |