LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 80.50 | 19.50 | 4170 | 6018 | 0.6945 | 0.8840 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 82.50 | 19.50 | 4313 | 6031 | 0.7166 | 0.8908 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 84.40 | 19.50 | 4479 | 6038 | 0.7429 | 0.8972 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 86.40 | 19.50 | 4667 | 6081 | 0.7680 | 0.9075 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 88.40 | 19.50 | 4840 | 6064 | 0.7983 | 0.9137 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 90.40 | 19.50 | 5027 | 6097 | 0.8245 | 0.9213 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 92.30 | 19.50 | 5215 | 6153 | 0.8474 | 0.9290 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 94.30 | 19.50 | 5403 | 6154 | 0.8774 | 0.9380 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 2.70 | 19.50 | 253 | 163 | 1.5179 | 0.6281 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 4.60 | 19.50 | 366 | 295 | 1.2347 | 0.5315 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 6.60 | 19.50 | 437 | 390 | 1.1191 | 0.5150 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 8.60 | 19.50 | 469 | 442 | 1.0622 | 0.5033 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.60 | 19.50 | 494 | 467 | 1.0580 | 0.5252 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 12.50 | 19.50 | 509 | 495 | 1.0280 | 0.5527 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 14.50 | 19.50 | 553 | 537 | 1.0285 | 0.5985 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 16.50 | 19.50 | 588 | 626 | 0.9427 | 0.6138 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 18.40 | 19.50 | 639 | 775 | 0.8283 | 0.6048 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 20.40 | 19.50 | 705 | 951 | 0.7493 | 0.6469 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 22.40 | 19.50 | 754 | 1150 | 0.6610 | 0.6356 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 24.30 | 19.50 | 772 | 1322 | 0.5815 | 0.6168 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 26.30 | 19.50 | 764 | 1491 | 0.5112 | 0.5967 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 28.30 | 19.50 | 773 | 1665 | 0.4641 | 0.5896 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 30.30 | 19.50 | 810 | 1887 | 0.4296 | 0.5882 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 32.20 | 19.50 | 820 | 2123 | 0.3867 | 0.5713 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 34.20 | 19.50 | 836 | 2452 | 0.3431 | 0.5666 |