LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 6.60 | 19.50 | 334 | 390 | 0.8545 | 0.4153 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 8.60 | 19.50 | 381 | 442 | 0.8633 | 0.4251 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 10.60 | 19.50 | 411 | 467 | 0.8812 | 0.4331 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 12.50 | 19.50 | 430 | 495 | 0.8676 | 0.4427 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 14.50 | 19.50 | 468 | 537 | 0.8715 | 0.4713 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 16.50 | 19.50 | 514 | 626 | 0.8223 | 0.4574 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 18.40 | 19.50 | 572 | 775 | 0.7393 | 0.4725 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 20.40 | 19.50 | 630 | 951 | 0.6641 | 0.4613 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 22.40 | 19.50 | 720 | 1150 | 0.6284 | 0.4992 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 24.30 | 19.50 | 845 | 1322 | 0.6371 | 0.5352 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 26.30 | 19.50 | 927 | 1491 | 0.6206 | 0.5421 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 28.30 | 19.50 | 1010 | 1665 | 0.6064 | 0.5443 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 30.30 | 19.50 | 1134 | 1887 | 0.6012 | 0.5781 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 32.20 | 19.50 | 1279 | 2123 | 0.6034 | 0.6014 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 34.20 | 19.50 | 1435 | 2452 | 0.5897 | 0.6109 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 36.20 | 19.50 | 1597 | 2641 | 0.6069 | 0.6195 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 38.10 | 19.50 | 1795 | 2867 | 0.6287 | 0.6563 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 40.10 | 19.50 | 2035 | 3104 | 0.6567 | 0.6829 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 42.10 | 19.50 | 2301 | 3461 | 0.6677 | 0.6861 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 44.00 | 19.50 | 2560 | 3824 | 0.6736 | 0.6987 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 46.00 | 19.50 | 2808 | 4146 | 0.6772 | 0.7067 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 48.00 | 19.50 | 3063 | 4441 | 0.6873 | 0.7115 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 50.00 | 19.50 | 3094 | 4744 | 0.6488 | 0.7000 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 51.90 | 19.50 | 3547 | 4974 | 0.7057 | 0.7133 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 53.90 | 19.50 | 3824 | 5154 | 0.7310 | 0.7432 |