LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 55.90 | 19.50 | 3828 | 5348 | 0.7043 | 0.7488 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 57.80 | 19.50 | 4437 | 5483 | 0.7906 | 0.7757 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 59.80 | 19.50 | 4776 | 5578 | 0.8364 | 0.7781 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 62.80 | 19.50 | 5266 | 5586 | 0.9252 | 0.9219 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 64.70 | 19.50 | 5624 | 5643 | 0.9794 | 0.9382 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 66.70 | 19.50 | 5909 | 5728 | 1.0142 | 0.9499 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 68.70 | 19.50 | 6204 | 5743 | 1.0628 | 0.9574 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 70.70 | 19.50 | 6447 | 5784 | 1.0983 | 0.9643 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 72.60 | 19.50 | 6672 | 5854 | 1.1260 | 0.9661 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 74.60 | 19.50 | 6867 | 5927 | 1.1456 | 0.9739 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 76.60 | 19.50 | 7096 | 5898 | 1.1929 | 0.9801 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 78.50 | 19.50 | 7264 | 5949 | 1.2104 | 0.9774 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 80.50 | 19.50 | 7408 | 6018 | 1.2218 | 0.9817 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 82.50 | 19.50 | 7516 | 6031 | 1.2380 | 0.9833 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 84.40 | 19.50 | 7522 | 6038 | 1.2402 | 0.9766 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 86.40 | 19.50 | 7403 | 6081 | 1.2138 | 0.9549 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 88.40 | 19.50 | 7418 | 6064 | 1.2225 | 0.9489 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 90.40 | 19.50 | 7412 | 6097 | 1.2163 | 0.9163 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 92.30 | 19.50 | 7447 | 6153 | 1.2117 | 0.8897 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 94.30 | 19.50 | 7375 | 6154 | 1.2015 | 0.8717 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 2.70 | 19.50 | 234 | 163 | 1.4322 | 0.6589 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 4.60 | 19.50 | 345 | 295 | 1.1632 | 0.5416 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 6.60 | 19.50 | 425 | 390 | 1.0897 | 0.5436 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 8.60 | 19.50 | 469 | 442 | 1.0606 | 0.5540 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 10.60 | 19.50 | 495 | 467 | 1.0603 | 0.5636 |