LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 94.30 | 19.50 | 6404 | 6154 | 1.0420 | 0.5396 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 2.70 | 19.50 | 221 | 163 | 1.3192 | 0.5892 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 4.60 | 19.50 | 337 | 295 | 1.1247 | 0.5044 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 6.60 | 19.50 | 418 | 390 | 1.0715 | 0.5187 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 8.60 | 19.50 | 469 | 442 | 1.0613 | 0.5140 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 10.60 | 19.50 | 500 | 467 | 1.0709 | 0.5382 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 12.50 | 19.50 | 538 | 495 | 1.0869 | 0.6210 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 14.50 | 19.50 | 594 | 537 | 1.1043 | 0.6599 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 16.50 | 19.50 | 675 | 626 | 1.0863 | 0.6640 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 18.40 | 19.50 | 829 | 775 | 1.0776 | 0.7288 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 20.40 | 19.50 | 945 | 951 | 1.0073 | 0.7078 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 22.40 | 19.50 | 1077 | 1150 | 0.9464 | 0.7332 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 24.30 | 19.50 | 1178 | 1322 | 0.8855 | 0.7407 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 26.30 | 19.50 | 1262 | 1491 | 0.8432 | 0.7435 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 28.30 | 19.50 | 1411 | 1665 | 0.8463 | 0.7479 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 30.30 | 19.50 | 1663 | 1887 | 0.8816 | 0.8002 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 32.20 | 19.50 | 1863 | 2123 | 0.8794 | 0.7998 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 34.20 | 19.50 | 2102 | 2452 | 0.8666 | 0.7860 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 36.20 | 19.50 | 2350 | 2641 | 0.8950 | 0.7761 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 38.10 | 19.50 | 2595 | 2867 | 0.9102 | 0.8206 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 40.10 | 19.50 | 2876 | 3104 | 0.9288 | 0.8216 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 42.10 | 19.50 | 3211 | 3461 | 0.9321 | 0.8338 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 44.00 | 19.50 | 3562 | 3824 | 0.9381 | 0.8339 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 46.00 | 19.50 | 3911 | 4146 | 0.9430 | 0.8367 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 48.00 | 19.50 | 4219 | 4441 | 0.9458 | 0.8432 |