LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 31.90 | 770.96 | 3444 | 3294 | 1.0485 | 1.0438 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 34.10 | 770.96 | 3730 | 3605 | 1.0377 | 1.0317 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 36.40 | 770.96 | 4124 | 3985 | 1.0375 | 1.0292 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 38.60 | 770.96 | 4542 | 4421 | 1.0300 | 1.0217 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 40.80 | 770.96 | 4932 | 4874 | 1.0144 | 1.0088 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 43.00 | 770.96 | 5393 | 5280 | 1.0235 | 1.0145 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 45.30 | 770.96 | 5742 | 5677 | 1.0134 | 1.0072 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 47.50 | 770.96 | 6169 | 6082 | 1.0163 | 1.0089 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 49.70 | 770.96 | 6672 | 6511 | 1.0263 | 1.0149 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 51.90 | 770.96 | 7218 | 6944 | 1.0407 | 1.0236 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 54.10 | 770.96 | 7683 | 7405 | 1.0388 | 1.0218 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 56.40 | 770.96 | 8211 | 7845 | 1.0480 | 1.0263 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 58.60 | 770.96 | 8668 | 8264 | 1.0502 | 1.0272 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 60.80 | 770.96 | 9159 | 8711 | 1.0526 | 1.0278 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 63.00 | 770.96 | 9607 | 9152 | 1.0508 | 1.0264 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 65.30 | 770.96 | 10029 | 9591 | 1.0465 | 1.0236 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 67.50 | 770.96 | 10383 | 9939 | 1.0452 | 1.0228 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 69.70 | 770.96 | 10742 | 10312 | 1.0419 | 1.0207 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 71.90 | 770.96 | 11066 | 10631 | 1.0410 | 1.0198 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 74.10 | 770.96 | 11386 | 10921 | 1.0426 | 1.0205 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 76.40 | 770.96 | 11639 | 11184 | 1.0407 | 1.0192 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 78.60 | 770.96 | 11962 | 11443 | 1.0454 | 1.0213 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 80.80 | 770.96 | 12288 | 11725 | 1.0479 | 1.0222 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 83.10 | 770.96 | 12569 | 12002 | 1.0471 | 1.0213 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 85.30 | 770.96 | 12831 | 12277 | 1.0451 | 1.0198 |