LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 67.50 | 770.96 | 3147 | 9939 | 0.3172 | 0.4616 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 69.70 | 770.96 | 3285 | 10312 | 0.3189 | 0.4708 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 71.90 | 770.96 | 3406 | 10631 | 0.3208 | 0.4782 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 74.10 | 770.96 | 3510 | 10921 | 0.3216 | 0.4836 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 76.40 | 770.96 | 3661 | 11184 | 0.3276 | 0.4951 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 78.60 | 770.96 | 3780 | 11443 | 0.3306 | 0.5020 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 80.80 | 770.96 | 3942 | 11725 | 0.3363 | 0.5127 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 83.10 | 770.96 | 4047 | 12002 | 0.3373 | 0.5170 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 85.30 | 770.96 | 4213 | 12277 | 0.3433 | 0.5270 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 87.50 | 770.96 | 4331 | 12567 | 0.3446 | 0.5322 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 2.90 | 770.96 | 871 | 886 | 0.9824 | 0.8118 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 5.10 | 770.96 | 973 | 984 | 0.9889 | 0.9422 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 7.30 | 770.96 | 1062 | 1067 | 0.9955 | 0.9819 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 9.60 | 770.96 | 1146 | 1178 | 0.9726 | 0.9129 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 11.90 | 770.96 | 1263 | 1319 | 0.9574 | 0.8900 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 14.10 | 770.96 | 1387 | 1478 | 0.9380 | 0.8675 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 16.40 | 770.96 | 1463 | 1625 | 0.9005 | 0.8139 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 18.60 | 770.96 | 1495 | 1786 | 0.8370 | 0.7268 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 20.80 | 770.96 | 1522 | 1959 | 0.7769 | 0.6577 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 23.00 | 770.96 | 1518 | 2193 | 0.6923 | 0.5667 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 25.30 | 770.96 | 1521 | 2456 | 0.6193 | 0.5013 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 27.50 | 770.96 | 1524 | 2754 | 0.5536 | 0.4490 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 29.70 | 770.96 | 1533 | 3022 | 0.5072 | 0.4170 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 31.90 | 770.96 | 1537 | 3294 | 0.4664 | 0.3893 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 34.10 | 770.96 | 1557 | 3605 | 0.4320 | 0.3712 |