LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 11.90 | 770.96 | 1212 | 1319 | 0.9215 | 0.8148 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 14.10 | 770.96 | 1350 | 1478 | 0.9141 | 0.8211 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 16.40 | 770.96 | 1395 | 1625 | 0.8603 | 0.7422 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 18.60 | 770.96 | 1451 | 1786 | 0.8144 | 0.6903 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 20.80 | 770.96 | 1455 | 1959 | 0.7448 | 0.6070 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 23.00 | 770.96 | 1446 | 2193 | 0.6610 | 0.5194 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 25.30 | 770.96 | 1429 | 2456 | 0.5830 | 0.4475 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 27.50 | 770.96 | 1451 | 2754 | 0.5284 | 0.4121 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 29.70 | 770.96 | 1531 | 3022 | 0.5085 | 0.4161 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 31.90 | 770.96 | 1546 | 3294 | 0.4712 | 0.3937 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 34.10 | 770.96 | 1600 | 3605 | 0.4455 | 0.3882 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 36.40 | 770.96 | 1657 | 3985 | 0.4170 | 0.3801 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 38.60 | 770.96 | 1674 | 4421 | 0.3797 | 0.3600 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 40.80 | 770.96 | 1790 | 4874 | 0.3684 | 0.3713 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 43.00 | 770.96 | 1859 | 5280 | 0.3532 | 0.3713 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 45.30 | 770.96 | 1990 | 5677 | 0.3515 | 0.3880 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 47.50 | 770.96 | 2084 | 6082 | 0.3436 | 0.3938 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 49.70 | 770.96 | 2204 | 6511 | 0.3392 | 0.4046 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 51.90 | 770.96 | 2328 | 6944 | 0.3360 | 0.4151 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 54.10 | 770.96 | 2440 | 7405 | 0.3304 | 0.4212 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 56.40 | 770.96 | 2608 | 7845 | 0.3332 | 0.4370 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 58.60 | 770.96 | 2671 | 8264 | 0.3241 | 0.4360 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 60.80 | 770.96 | 2803 | 8711 | 0.3227 | 0.4445 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 63.00 | 770.96 | 2897 | 9152 | 0.3174 | 0.4462 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 65.30 | 770.96 | 3042 | 9591 | 0.3179 | 0.4561 |