LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 63.00 | 770.96 | 8899 | 9152 | 0.9732 | 0.9834 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 65.30 | 770.96 | 9245 | 9591 | 0.9645 | 0.9784 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 67.50 | 770.96 | 9638 | 9939 | 0.9702 | 0.9819 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 69.70 | 770.96 | 9999 | 10312 | 0.9699 | 0.9818 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 71.90 | 770.96 | 10344 | 10631 | 0.9732 | 0.9835 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 74.10 | 770.96 | 10584 | 10921 | 0.9693 | 0.9812 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 76.40 | 770.96 | 10861 | 11184 | 0.9713 | 0.9822 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 78.60 | 770.96 | 11113 | 11443 | 0.9714 | 0.9820 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 80.80 | 770.96 | 11400 | 11725 | 0.9724 | 0.9823 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 83.10 | 770.96 | 11653 | 12002 | 0.9710 | 0.9813 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 85.30 | 770.96 | 11896 | 12277 | 0.9690 | 0.9801 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 87.50 | 770.96 | 12164 | 12567 | 0.9679 | 0.9791 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 2.90 | 770.96 | 943 | 886 | 1.0662 | 2.3433 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 5.10 | 770.96 | 1051 | 984 | 1.0711 | 1.6265 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 7.30 | 770.96 | 1141 | 1067 | 1.0715 | 1.3914 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 9.60 | 770.96 | 1255 | 1178 | 1.0693 | 1.2830 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 11.90 | 770.96 | 1402 | 1319 | 1.0663 | 1.1957 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 14.10 | 770.96 | 1575 | 1478 | 1.0665 | 1.1473 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 16.40 | 770.96 | 1757 | 1625 | 1.0843 | 1.1631 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 18.60 | 770.96 | 1930 | 1786 | 1.0834 | 1.1404 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 20.80 | 770.96 | 2100 | 1959 | 1.0746 | 1.1114 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 23.00 | 770.96 | 2316 | 2193 | 1.0587 | 1.0769 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 25.30 | 770.96 | 2588 | 2456 | 1.0560 | 1.0655 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 27.50 | 770.96 | 2865 | 2754 | 1.0432 | 1.0456 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 29.70 | 770.96 | 3160 | 3022 | 1.0484 | 1.0470 |