LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 7.30 | 770.96 | 1019 | 1067 | 0.9560 | 0.8638 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 9.60 | 770.96 | 1111 | 1178 | 0.9453 | 0.8505 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 11.90 | 770.96 | 1249 | 1319 | 0.9489 | 0.8798 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 14.10 | 770.96 | 1401 | 1478 | 0.9482 | 0.8921 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 16.40 | 770.96 | 1559 | 1625 | 0.9614 | 0.9315 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 18.60 | 770.96 | 1715 | 1786 | 0.9616 | 0.9386 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 20.80 | 770.96 | 1865 | 1959 | 0.9538 | 0.9316 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 23.00 | 770.96 | 2067 | 2193 | 0.9445 | 0.9253 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 25.30 | 770.96 | 2315 | 2456 | 0.9441 | 0.9319 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 27.50 | 770.96 | 2598 | 2754 | 0.9449 | 0.9388 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 29.70 | 770.96 | 2866 | 3022 | 0.9500 | 0.9479 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 31.90 | 770.96 | 3127 | 3294 | 0.9514 | 0.9518 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 34.10 | 770.96 | 3435 | 3605 | 0.9548 | 0.9577 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 36.40 | 770.96 | 3797 | 3985 | 0.9543 | 0.9596 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 38.60 | 770.96 | 4157 | 4421 | 0.9417 | 0.9518 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 40.80 | 770.96 | 4598 | 4874 | 0.9449 | 0.9568 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 43.00 | 770.96 | 4972 | 5280 | 0.9430 | 0.9570 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 45.30 | 770.96 | 5350 | 5677 | 0.9438 | 0.9590 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 47.50 | 770.96 | 5777 | 6082 | 0.9510 | 0.9652 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 49.70 | 770.96 | 6205 | 6511 | 0.9538 | 0.9684 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 51.90 | 770.96 | 6656 | 6944 | 0.9592 | 0.9725 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 54.10 | 770.96 | 7119 | 7405 | 0.9621 | 0.9752 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 56.40 | 770.96 | 7558 | 7845 | 0.9641 | 0.9771 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 58.60 | 770.96 | 8010 | 8264 | 0.9701 | 0.9811 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 60.80 | 770.96 | 8459 | 8711 | 0.9720 | 0.9824 |