LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 87.50 | 770.96 | 13209 | 12567 | 1.0511 | 1.0222 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 2.90 | 770.96 | 855 | 886 | 0.9653 | 0.6660 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 5.10 | 770.96 | 939 | 984 | 0.9536 | 0.7398 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 7.30 | 770.96 | 1027 | 1067 | 0.9622 | 0.8417 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 9.60 | 770.96 | 1121 | 1178 | 0.9518 | 0.8433 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 11.90 | 770.96 | 1272 | 1319 | 0.9646 | 0.9085 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 14.10 | 770.96 | 1425 | 1478 | 0.9642 | 0.9233 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 16.40 | 770.96 | 1585 | 1625 | 0.9758 | 0.9547 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 18.60 | 770.96 | 1720 | 1786 | 0.9631 | 0.9391 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 20.80 | 770.96 | 1861 | 1959 | 0.9502 | 0.9257 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 23.00 | 770.96 | 2040 | 2193 | 0.9305 | 0.9067 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 25.30 | 770.96 | 2279 | 2456 | 0.9281 | 0.9126 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 27.50 | 770.96 | 2532 | 2754 | 0.9193 | 0.9104 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 29.70 | 770.96 | 2787 | 3022 | 0.9221 | 0.9193 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 31.90 | 770.96 | 3028 | 3294 | 0.9196 | 0.9217 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 34.10 | 770.96 | 3289 | 3605 | 0.9123 | 0.9191 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 36.40 | 770.96 | 3579 | 3985 | 0.8981 | 0.9112 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 38.60 | 770.96 | 3944 | 4421 | 0.8919 | 0.9110 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 40.80 | 770.96 | 4291 | 4874 | 0.8802 | 0.9060 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 43.00 | 770.96 | 4657 | 5280 | 0.8821 | 0.9113 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 45.30 | 770.96 | 4999 | 5677 | 0.8806 | 0.9136 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 47.50 | 770.96 | 5336 | 6082 | 0.8772 | 0.9138 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 49.70 | 770.96 | 5723 | 6511 | 0.8789 | 0.9177 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 51.90 | 770.96 | 6096 | 6944 | 0.8779 | 0.9194 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 54.10 | 770.96 | 6481 | 7405 | 0.8750 | 0.9197 |