LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 16.00 | 771.67 | 1569 | 1585 | 0.9896 | 0.9800 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 16.00 | 771.67 | 1789 | 1585 | 1.1284 | 1.2465 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.22 | 771.67 | 1675 | 1741 | 0.9619 | 0.9349 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.22 | 771.67 | 1826 | 1741 | 1.0486 | 1.0825 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 20.44 | 771.67 | 1806 | 1910 | 0.9451 | 0.9155 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 20.44 | 771.67 | 2068 | 1910 | 1.0822 | 1.1245 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 22.66 | 771.67 | 1998 | 2141 | 0.9330 | 0.9080 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 22.66 | 771.67 | 2244 | 2141 | 1.0479 | 1.0645 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 24.89 | 771.67 | 2194 | 2397 | 0.9150 | 0.8943 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 24.89 | 771.67 | 2466 | 2397 | 1.0285 | 1.0346 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 27.11 | 771.67 | 2416 | 2675 | 0.9031 | 0.8896 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 27.11 | 771.67 | 2761 | 2675 | 1.0321 | 1.0355 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 29.33 | 771.67 | 2597 | 2939 | 0.8835 | 0.8757 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 29.33 | 771.67 | 3015 | 2939 | 1.0257 | 1.0265 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 31.55 | 771.67 | 2818 | 3196 | 0.8815 | 0.8807 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 31.55 | 771.67 | 3256 | 3196 | 1.0185 | 1.0180 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 33.78 | 771.67 | 3026 | 3499 | 0.8647 | 0.8710 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 33.78 | 771.67 | 3514 | 3499 | 1.0041 | 1.0038 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 36.00 | 771.67 | 3279 | 3884 | 0.8441 | 0.8598 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 36.00 | 771.67 | 3777 | 3884 | 0.9723 | 0.9760 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 38.22 | 771.67 | 3527 | 4299 | 0.8203 | 0.8464 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 38.22 | 771.67 | 4155 | 4299 | 0.9664 | 0.9726 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 40.44 | 771.67 | 3855 | 4738 | 0.8136 | 0.8485 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 40.44 | 771.67 | 4504 | 4738 | 0.9505 | 0.9616 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 42.67 | 771.67 | 4147 | 5155 | 0.8043 | 0.8472 | MN20160304_L01 | H11 |