LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 73.76 | 771.67 | 9293 | 10851 | 0.8564 | 0.9203 | MN20160304_L01 | D12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 76.02 | 771.67 | 9733 | 11106 | 0.8763 | 0.9325 | MN20160304_L01 | C19 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 76.02 | 771.67 | 9459 | 11106 | 0.8516 | 0.9182 | MN20160304_L01 | D12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 78.25 | 771.67 | 9988 | 11367 | 0.8786 | 0.9344 | MN20160304_L01 | C19 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 78.25 | 771.67 | 9622 | 11367 | 0.8464 | 0.9159 | MN20160304_L01 | D12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 80.48 | 771.67 | 10260 | 11685 | 0.8781 | 0.9347 | MN20160304_L01 | C19 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 80.48 | 771.67 | 9738 | 11685 | 0.8334 | 0.9092 | MN20160304_L01 | D12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 82.69 | 771.67 | 10613 | 11974 | 0.8863 | 0.9399 | MN20160304_L01 | C19 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 82.69 | 771.67 | 10026 | 11974 | 0.8373 | 0.9122 | MN20160304_L01 | D12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 84.92 | 771.67 | 10875 | 12266 | 0.8865 | 0.9406 | MN20160304_L01 | C19 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 84.92 | 771.67 | 10184 | 12266 | 0.8302 | 0.9089 | MN20160304_L01 | D12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 87.14 | 771.67 | 11203 | 12592 | 0.8897 | 0.9428 | MN20160304_L01 | C19 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 87.14 | 771.67 | 10289 | 12592 | 0.8171 | 0.9022 | MN20160304_L01 | D12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 2.49 | 771.67 | 839 | 867 | 0.9669 | 0.6391 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 2.49 | 771.67 | 952 | 867 | 1.0971 | 2.4572 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 4.71 | 771.67 | 934 | 956 | 0.9766 | 0.8528 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 4.71 | 771.67 | 1062 | 956 | 1.1104 | 1.8053 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 6.94 | 771.67 | 1027 | 1045 | 0.9827 | 0.9216 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 6.94 | 771.67 | 1134 | 1045 | 1.0850 | 1.4100 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 9.16 | 771.67 | 1113 | 1138 | 0.9776 | 0.9209 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 9.16 | 771.67 | 1240 | 1138 | 1.0892 | 1.3288 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 11.56 | 771.67 | 1294 | 1280 | 1.0104 | 1.0286 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 11.56 | 771.67 | 1405 | 1280 | 1.0971 | 1.2705 | MN20160304_L01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 13.78 | 771.67 | 1426 | 1459 | 0.9769 | 0.9498 | MN20160304_L01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 13.78 | 771.67 | 1606 | 1459 | 1.1002 | 1.2188 | MN20160304_L01 | M13 |