LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 80.48 | 771.67 | 5946 | 11685 | 0.5089 | 0.6834 | MN20160304_L01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 80.48 | 771.67 | 7654 | 11685 | 0.6550 | 0.7954 | MN20160304_L01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 82.69 | 771.67 | 7174 | 11974 | 0.5991 | 0.7571 | MN20160304_L01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 82.69 | 771.67 | 5999 | 11974 | 0.5010 | 0.6794 | MN20160304_L01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 82.69 | 771.67 | 7990 | 11974 | 0.6673 | 0.8056 | MN20160304_L01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 84.92 | 771.67 | 7473 | 12266 | 0.6092 | 0.7664 | MN20160304_L01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 84.92 | 771.67 | 6119 | 12266 | 0.4988 | 0.6801 | MN20160304_L01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 84.92 | 771.67 | 8387 | 12266 | 0.6837 | 0.8182 | MN20160304_L01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 87.14 | 771.67 | 7832 | 12592 | 0.6220 | 0.7776 | MN20160304_L01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 87.14 | 771.67 | 6208 | 12592 | 0.4930 | 0.6780 | MN20160304_L01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 87.14 | 771.67 | 8762 | 12592 | 0.6958 | 0.8278 | MN20160304_L01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 2.49 | 771.67 | 888 | 867 | 1.0233 | 1.2920 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 2.49 | 771.67 | 985 | 867 | 1.1351 | 3.2281 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 4.71 | 771.67 | 993 | 956 | 1.0383 | 1.2581 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 4.71 | 771.67 | 502 | 956 | 0.5249 | -0.7506 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 6.94 | 771.67 | 1081 | 1045 | 1.0343 | 1.1603 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 6.94 | 771.67 | 1188 | 1045 | 1.1367 | 1.6803 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 9.16 | 771.67 | 1177 | 1138 | 1.0338 | 1.1221 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 9.16 | 771.67 | 1285 | 1138 | 1.1287 | 1.4816 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 11.56 | 771.67 | 1343 | 1280 | 1.0487 | 1.1345 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 11.56 | 771.67 | 1441 | 1280 | 1.1252 | 1.3504 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 13.78 | 771.67 | 1485 | 1459 | 1.0173 | 1.0376 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 13.78 | 771.67 | 1644 | 1459 | 1.1262 | 1.2759 | MN20160304_L01 | N13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 16.00 | 771.67 | 1604 | 1585 | 1.0117 | 1.0225 | MN20160304_L01 | I11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 16.00 | 771.67 | 1787 | 1585 | 1.1271 | 1.2441 | MN20160304_L01 | N13 |