LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 70.05 | 770.25 | 1420 | 10413 | 0.1364 | 0.1768 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 72.27 | 770.25 | 1218 | 10730 | 0.1135 | 0.1282 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 72.27 | 770.25 | 1406 | 10730 | 0.1310 | 0.1716 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 74.50 | 770.25 | 1211 | 10991 | 0.1102 | 0.1252 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 74.50 | 770.25 | 1421 | 10991 | 0.1293 | 0.1732 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 76.75 | 770.25 | 1206 | 11262 | 0.1071 | 0.1228 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 76.75 | 770.25 | 1419 | 11262 | 0.1260 | 0.1710 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 78.98 | 770.25 | 1214 | 11518 | 0.1054 | 0.1237 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 78.98 | 770.25 | 1425 | 11518 | 0.1237 | 0.1708 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 81.20 | 770.25 | 1201 | 11766 | 0.1021 | 0.1196 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 81.20 | 770.25 | 1434 | 11766 | 0.1219 | 0.1712 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 83.42 | 770.25 | 1206 | 12031 | 0.1002 | 0.1197 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 83.42 | 770.25 | 1415 | 12031 | 0.1176 | 0.1658 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 85.64 | 770.25 | 1225 | 12287 | 0.0997 | 0.1231 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 85.64 | 770.25 | 1424 | 12287 | 0.1159 | 0.1663 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.86 | 770.25 | 1212 | 12543 | 0.0966 | 0.1192 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.86 | 770.25 | 1422 | 12543 | 0.1134 | 0.1645 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 3.21 | 770.25 | 902 | 904 | 0.9971 | 0.9751 | MN20160304_L02 | C18 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 3.21 | 770.25 | 1074 | 904 | 1.1872 | 3.1909 | MN20160304_L02 | M14 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 5.44 | 770.25 | 975 | 1012 | 0.9627 | 0.8166 | MN20160304_L02 | C18 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 5.44 | 770.25 | 1182 | 1012 | 1.1671 | 1.9580 | MN20160304_L02 | M14 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 7.66 | 770.25 | 1030 | 1090 | 0.9450 | 0.7863 | MN20160304_L02 | C18 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 7.66 | 770.25 | 1287 | 1090 | 1.1807 | 1.7865 | MN20160304_L02 | M14 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 10.06 | 770.25 | 1139 | 1218 | 0.9348 | 0.8061 | MN20160304_L02 | C18 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 10.06 | 770.25 | 1422 | 1218 | 1.1670 | 1.5258 | MN20160304_L02 | M14 |