LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 43.39 | 770.25 | 1227 | 5404 | 0.2270 | 0.1802 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 43.39 | 770.25 | 1379 | 5404 | 0.2552 | 0.2302 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 45.61 | 770.25 | 1216 | 5813 | 0.2092 | 0.1695 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 45.61 | 770.25 | 1371 | 5813 | 0.2359 | 0.2186 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 47.83 | 770.25 | 1229 | 6223 | 0.1975 | 0.1677 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 47.83 | 770.25 | 1378 | 6223 | 0.2214 | 0.2129 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 50.05 | 770.25 | 1225 | 6629 | 0.1848 | 0.1612 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 50.05 | 770.25 | 1388 | 6629 | 0.2094 | 0.2088 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 52.27 | 770.25 | 1226 | 7058 | 0.1737 | 0.1565 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 52.27 | 770.25 | 1392 | 7058 | 0.1972 | 0.2034 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 54.49 | 770.25 | 1222 | 7555 | 0.1617 | 0.1504 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 54.49 | 770.25 | 1409 | 7555 | 0.1865 | 0.2012 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 56.71 | 770.25 | 1239 | 8001 | 0.1548 | 0.1512 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 56.71 | 770.25 | 1395 | 8001 | 0.1743 | 0.1923 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 58.94 | 770.25 | 1233 | 8444 | 0.1460 | 0.1459 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 58.94 | 770.25 | 1414 | 8444 | 0.1675 | 0.1923 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 61.16 | 770.25 | 1215 | 8892 | 0.1366 | 0.1379 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 61.16 | 770.25 | 1412 | 8892 | 0.1588 | 0.1874 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 63.39 | 770.25 | 1208 | 9326 | 0.1295 | 0.1332 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 63.39 | 770.25 | 1411 | 9326 | 0.1513 | 0.1832 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 65.61 | 770.25 | 1215 | 9736 | 0.1248 | 0.1326 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 65.61 | 770.25 | 1413 | 9736 | 0.1451 | 0.1803 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 67.83 | 770.25 | 1197 | 10078 | 0.1188 | 0.1262 | MN20160304_L02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 67.83 | 770.25 | 1400 | 10078 | 0.1389 | 0.1748 | MN20160304_L02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 70.05 | 770.25 | 1209 | 10413 | 0.1161 | 0.1275 | MN20160304_L02 | I09 |