LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)

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Cell Small Molecule Small Mol Concentration (uM) Time Point (hr) Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value Assay Plate Assay Well
MCF 10A-H2B-mCherry Trametinib
1
 70.05 770.25 1420 10413 0.1364 0.1768
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 72.27 770.25 1218 10730 0.1135 0.1282
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 72.27 770.25 1406 10730 0.1310 0.1716
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 74.50 770.25 1211 10991 0.1102 0.1252
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 74.50 770.25 1421 10991 0.1293 0.1732
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 76.75 770.25 1206 11262 0.1071 0.1228
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 76.75 770.25 1419 11262 0.1260 0.1710
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 78.98 770.25 1214 11518 0.1054 0.1237
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 78.98 770.25 1425 11518 0.1237 0.1708
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 81.20 770.25 1201 11766 0.1021 0.1196
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 81.20 770.25 1434 11766 0.1219 0.1712
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 83.42 770.25 1206 12031 0.1002 0.1197
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 83.42 770.25 1415 12031 0.1176 0.1658
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 85.64 770.25 1225 12287 0.0997 0.1231
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 85.64 770.25 1424 12287 0.1159 0.1663
MN20160304_L02
I10
MCF 10A-H2B-mCherry Trametinib
1
 87.86 770.25 1212 12543 0.0966 0.1192
MN20160304_L02
I09
MCF 10A-H2B-mCherry Trametinib
1
 87.86 770.25 1422 12543 0.1134 0.1645
MN20160304_L02
I10
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 3.21 770.25 902 904 0.9971 0.9751
MN20160304_L02
C18
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 3.21 770.25 1074 904 1.1872 3.1909
MN20160304_L02
M14
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 5.44 770.25 975 1012 0.9627 0.8166
MN20160304_L02
C18
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 5.44 770.25 1182 1012 1.1671 1.9580
MN20160304_L02
M14
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 7.66 770.25 1030 1090 0.9450 0.7863
MN20160304_L02
C18
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 7.66 770.25 1287 1090 1.1807 1.7865
MN20160304_L02
M14
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 10.06 770.25 1139 1218 0.9348 0.8061
MN20160304_L02
C18
MCF 10A-H2B-mCherry Vorinostat
0.0033333
 10.06 770.25 1422 1218 1.1670 1.5258
MN20160304_L02
M14