Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 7109 392 2.1297 1.5833 0.0551 0.0617
MZ7-mel Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 1 3616 276 1.0590 1.5833 0.0763 0.0617
MZ7-mel Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 2 5203 279 1.5612 1.5833 0.0536 0.0617
MZ7-mel Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 2 4806 288 1.4736 1.4168 0.0599 0.0618
MZ7-mel Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 1 2761 200 0.8353 1.4168 0.0724 0.0618
MZ7-mel Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 3 6287 334 1.9416 1.4168 0.0531 0.0618
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 1 4085 262 1.1029 1.3927 0.0641 0.0616
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 3 5704 336 1.5486 1.3927 0.0589 0.0616
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 2 5640 348 1.5267 1.3927 0.0617 0.0616
MMAC-SF Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 2 1516 54 1.4357 1.3028 0.0356 0.0415
MMAC-SF Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 1 1158 56 1.0822 1.3028 0.0484 0.0415
MMAC-SF Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 1476 60 1.3905 1.3028 0.0407 0.0415
MMAC-SF Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 3 1846 89 1.4019 1.3011 0.0482 0.0459
MMAC-SF Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 1 1511 68 1.1513 1.3011 0.0450 0.0459
MMAC-SF Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 2 1771 79 1.3500 1.3011 0.0446 0.0459
MMAC-SF Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 1 1207 52 1.1694 1.2926 0.0431 0.0509
MMAC-SF Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 3 1432 72 1.3770 1.2926 0.0503 0.0509
MMAC-SF Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 2 1398 83 1.3314 1.2926 0.0594 0.0509
MZ7-mel Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 3 6060 359 1.2527 1.1499 0.0592 0.0651
MZ7-mel Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 1 4690 306 0.9633 1.1499 0.0652 0.0651
MZ7-mel Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 2 6042 428 1.2336 1.1499 0.0708 0.0651
MMAC-SF Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 1 1508 67 0.8879 1.1047 0.0444 0.0462
MMAC-SF Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 2 2014 89 1.1861 1.1047 0.0442 0.0462
MMAC-SF Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 3 2119 106 1.2403 1.1047 0.0500 0.0462
MMAC-SF Vemurafenib Dasatinib 0.000 0.316
uM
 72
hr
 2 1603 97 1.1534 1.0853 0.0605 0.0619
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