Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
WM-115 Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 3981 292 0.9331 0.9197 0.0733 0.0725
WM-115 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 1 3766 260 0.8868 0.8594 0.0690 0.0671
WM-115 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 2 3687 223 0.8761 0.8594 0.0605 0.0671
WM-115 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 3 3472 249 0.8152 0.8594 0.0717 0.0671
WM-115 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 1 3379 380 0.7585 0.7158 0.1125 0.1036
WM-115 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 2 3250 329 0.7388 0.7158 0.1012 0.1036
WM-115 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 3 2846 276 0.6500 0.7158 0.0970 0.1036
WM-115 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 1 3490 205 0.8309 0.8272 0.0587 0.0678
WM-115 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 2 3291 245 0.7704 0.8272 0.0744 0.0678
WM-115 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 3 3744 263 0.8804 0.8272 0.0702 0.0678
WM-115 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 1 3055 234 0.7135 0.7245 0.0766 0.0810
WM-115 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 2 3200 257 0.7444 0.7245 0.0803 0.0810
WM-115 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 3 3095 266 0.7155 0.7245 0.0859 0.0810
WM-115 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 1 3214 278 0.7426 0.7117 0.0865 0.0820
WM-115 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 2 3209 265 0.7446 0.7117 0.0826 0.0820
WM-115 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 3 2774 213 0.6478 0.7117 0.0768 0.0820
WM-115 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 1 2726 316 0.6096 0.5849 0.1159 0.1183
WM-115 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 2 2638 323 0.5855 0.5849 0.1224 0.1183
WM-115 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 3 2505 292 0.5597 0.5849 0.1166 0.1183
WM-115 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 1 2777 232 0.6437 0.6349 0.0835 0.0855
WM-115 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 2 2702 244 0.6217 0.6349 0.0903 0.0855
WM-115 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 3 2755 228 0.6392 0.6349 0.0828 0.0855
WM-115 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 1 2487 271 0.5605 0.5897 0.1090 0.1058
WM-115 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 2 2551 268 0.5774 0.5897 0.1051 0.1058
WM-115 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 3 2784 288 0.6313 0.5897 0.1034 0.1058