Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A-375 | Vemurafenib | PF562271 | 0.000 | 0.000 | uM | 72 | hr | 1 | 19613 | 936 | 1.0160 | 1.0000 | 0.0477 | 0.0485 |
| A-375 | Vemurafenib | Saracatinib | 0.000 | 0.000 | uM | 72 | hr | 3 | 19884 | 1032 | 0.9869 | 1.0000 | 0.0519 | 0.0527 |
| A-375 | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 1 | 19971 | 929 | 0.9642 | 1.0000 | 0.0465 | 0.0504 |
| A-375 | Vemurafenib | Saracatinib | 0.000 | 0.000 | uM | 72 | hr | 2 | 20251 | 1109 | 1.0021 | 1.0000 | 0.0548 | 0.0527 |
| A-375 | Vemurafenib | Saracatinib | 0.000 | 0.000 | uM | 72 | hr | 1 | 20360 | 1046 | 1.0111 | 1.0000 | 0.0514 | 0.0527 |
| A-375 | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 2 | 20940 | 1098 | 1.0048 | 1.0000 | 0.0524 | 0.0504 |
| A-375 | Vemurafenib | Defactinib | 0.000 | 0.000 | uM | 72 | hr | 2 | 21096 | 999 | 0.9631 | 1.0000 | 0.0474 | 0.0468 |
| A-375 | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 3 | 21481 | 1121 | 1.0310 | 1.0000 | 0.0522 | 0.0504 |
| A-375 | Vemurafenib | Defactinib | 0.000 | 0.000 | uM | 72 | hr | 1 | 22233 | 990 | 1.0180 | 1.0000 | 0.0445 | 0.0468 |
| A-375 | Vemurafenib | Defactinib | 0.000 | 0.000 | uM | 72 | hr | 3 | 22342 | 1082 | 1.0188 | 1.0000 | 0.0484 | 0.0468 |