Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 2 808 122 0.6736 0.6759 0.1510 0.1363
COLO 858 Vemurafenib Defactinib 3.160 3.160
uM
 72
hr
 2 809 781 0.0033 0.0047 0.9654 0.9535
COLO 858 Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 3 810 688 0.0207 0.0199 0.8494 0.8770
MMAC-SF Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 1 811 41 0.7796 0.6166 0.0506 0.0527
MMAC-SF Vemurafenib Defactinib 3.160 0.000
uM
 72
hr
 3 816 378 0.2699 0.2403 0.4632 0.4433
COLO 858 Vemurafenib JNK-IN-8 1.000 3.160
uM
 72
hr
 3 817 651 0.0275 0.0307 0.7968 0.7891
MMAC-SF Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 1 818 40 0.7640 0.6789 0.0489 0.0471
MMAC-SF Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 1 819 228 0.4715 0.3311 0.2784 0.2885
MMAC-SF Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 2 820 119 0.5593 0.5335 0.1451 0.1422
MZ7-mel Vemurafenib Dasatinib 1.000 3.160
uM
 72
hr
 3 820 65 0.1518 0.1839 0.0793 0.0837
MMAC-SF Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 1 823 140 0.5449 0.4894 0.1701 0.1367
MMAC-SF Vemurafenib Defactinib 0.316 1.000
uM
 72
hr
 2 826 215 0.3765 0.3619 0.2603 0.2613
MMAC-SF Vemurafenib Defactinib 1.000 1.000
uM
 72
hr
 1 828 289 0.3321 0.2820 0.3490 0.3755
COLO 858 Vemurafenib Belinostat 0.000 1.000
uM
 72
hr
 3 831 298 0.1223 0.1295 0.3586 0.3690
MZ7-mel Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 1 832 108 0.2361 0.2764 0.1298 0.1279
MMAC-SF Vemurafenib PF562271 0.316 0.000
uM
 72
hr
 2 832 118 0.7229 0.6679 0.1418 0.1517
COLO 858 Vemurafenib JNK-IN-8 1.000 0.316
uM
 72
hr
 2 832 414 0.0693 0.0722 0.4976 0.5757
COLO 858 Vemurafenib PF562271 3.160 1.000
uM
 72
hr
 2 832 777 0.0099 0.0092 0.9339 0.9423
COLO 858 Vemurafenib PF562271 3.160 0.316
uM
 72
hr
 3 833 776 0.0103 0.0125 0.9316 0.9029
COLO 858 Vemurafenib PF562271 1.000 1.000
uM
 72
hr
 2 833 687 0.0263 0.0248 0.8247 0.8407
COLO 858 Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 3 835 731 0.0176 0.0171 0.8754 0.8905
MMAC-SF Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 2 837 30 0.4972 0.4909 0.0358 0.0363
MZ7-mel Vemurafenib Defactinib 3.160 0.316
uM
 72
hr
 1 837 184 0.1435 0.1699 0.2198 0.2362
MZ7-mel Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 1 839 282 0.1817 0.3021 0.3361 0.3372
COLO 858 Vemurafenib JNK-IN-8 1.000 3.160
uM
 72
hr
 2 839 656 0.0303 0.0307 0.7819 0.7891