Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
A-375 Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 2 14559 660 0.7276 0.7489 0.0453 0.0459
A-375 Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 1 16059 813 0.7981 0.7489 0.0506 0.0459
A-375 Vemurafenib Saracatinib 0.000 0.000
uM
 72
hr
 3 19884 1032 0.9869 1.0000 0.0519 0.0527
A-375 Vemurafenib Saracatinib 0.000 0.000
uM
 72
hr
 2 20251 1109 1.0021 1.0000 0.0548 0.0527
A-375 Vemurafenib Saracatinib 0.000 0.000
uM
 72
hr
 1 20360 1046 1.0111 1.0000 0.0514 0.0527
MMAC-SF Vemurafenib Saracatinib 0.000 0.000
uM
 72
hr
 1 1135 66 0.8529 1.0000 0.0581 0.0496
MMAC-SF Vemurafenib Saracatinib 0.000 0.000
uM
 72
hr
 2 1504 69 1.1449 1.0000 0.0459 0.0496
MMAC-SF Vemurafenib Saracatinib 0.000 0.000
uM
 72
hr
 3 1315 59 1.0021 1.0000 0.0449 0.0496
MMAC-SF Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 1 1511 68 1.1513 1.3011 0.0450 0.0459
MMAC-SF Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 2 1771 79 1.3500 1.3011 0.0446 0.0459
MMAC-SF Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 3 1846 89 1.4019 1.3011 0.0482 0.0459
MMAC-SF Vemurafenib Saracatinib 0.000 1.000
uM
 72
hr
 1 1386 59 1.0588 0.8133 0.0426 0.0417
MMAC-SF Vemurafenib Saracatinib 0.000 1.000
uM
 72
hr
 2 956 43 0.7285 0.8133 0.0450 0.0417
MMAC-SF Vemurafenib Saracatinib 0.000 1.000
uM
 72
hr
 3 850 32 0.6527 0.8133 0.0376 0.0417
MMAC-SF Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 1 1325 58 1.0109 0.8059 0.0438 0.0432
MMAC-SF Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 2 1146 49 0.8753 0.8059 0.0428 0.0432
MMAC-SF Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 3 696 30 0.5314 0.8059 0.0431 0.0432
MMAC-SF Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 1 981 39 0.7516 0.7976 0.0398 0.0486
MMAC-SF Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 2 1126 71 0.8418 0.7976 0.0631 0.0486
MMAC-SF Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 3 1047 45 0.7995 0.7976 0.0430 0.0486
MMAC-SF Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 1 1049 35 0.8090 0.9306 0.0334 0.0304
MMAC-SF Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 2 1347 40 1.0428 0.9306 0.0297 0.0304
MMAC-SF Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 3 1212 34 0.9399 0.9306 0.0281 0.0304
MMAC-SF Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 1 1024 31 0.7923 0.6896 0.0303 0.0319
MMAC-SF Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 2 984 41 0.7524 0.6896 0.0417 0.0319