Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
WM-115 Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 3 1717 570 0.2863 0.2911 0.3320 0.3460
WM-115 Vemurafenib Belinostat 1.000 0.000
uM
 72
hr
 3 2479 297 0.6256 0.6049 0.1198 0.1230
MZ7-mel Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 3 1210 79 0.2274 0.3143 0.0653 0.0600
WM-115 Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 3 1661 650 0.2524 0.2711 0.3913 0.3806
COLO 858 Vemurafenib Belinostat 0.000 0.000
uM
 72
hr
 3 5258 859 1.0093 1.0000 0.1634 0.1617
MZ7-mel Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 3 1148 60 0.2188 0.2758 0.0523 0.0483
WM-115 Vemurafenib Dasatinib 0.316 0.000
uM
 72
hr
 3 3086 246 0.7089 0.7092 0.0797 0.0818
A-375 Vemurafenib PF562271 0.316 0.000
uM
 72
hr
 3 4571 110 0.2427 0.2505 0.0241 0.0221
MZ7-mel Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 3 2462 408 0.4131 0.3589 0.1657 0.1593
WM-115 Vemurafenib Dasatinib 0.100 3.160
uM
 72
hr
 3 1841 377 0.3655 0.3432 0.2048 0.2379