Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 1476 60 1.3905 1.3028 0.0407 0.0415
MMAC-SF Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 3 1846 89 1.4019 1.3011 0.0482 0.0459
MMAC-SF Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 2 1516 54 1.4357 1.3028 0.0356 0.0415
MZ7-mel Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 1 4872 354 1.4736 0.9734 0.0727 0.0805
MZ7-mel Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 2 4806 288 1.4736 1.4168 0.0599 0.0618
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 2 5640 348 1.5267 1.3927 0.0617 0.0616
MZ7-mel Vemurafenib PF562271 0.000 0.316
uM
 72
hr
 3 5704 336 1.5486 1.3927 0.0589 0.0616
MZ7-mel Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 2 5203 279 1.5612 1.5833 0.0536 0.0617
MZ7-mel Vemurafenib Saracatinib 0.000 0.316
uM
 72
hr
 3 6287 334 1.9416 1.4168 0.0531 0.0618
MZ7-mel Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 7109 392 2.1297 1.5833 0.0551 0.0617