Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib Belinostat 0.316 1.000
uM
 72
hr
 3 955 569 0.0886 0.1069 0.5958 0.5774
COLO 858 Vemurafenib I-BET151 3.160 1.000
uM
 72
hr
 2 1381 996 0.0890 0.0871 0.7212 0.7176
A-375 Vemurafenib Defactinib 3.160 1.000
uM
 72
hr
 2 2192 327 0.0894 0.0857 0.1492 0.1490
A-375 Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 1 2168 298 0.0896 0.0889 0.1375 0.1262
COLO 858 Vemurafenib I-BET151 0.316 1.000
uM
 72
hr
 3 1034 645 0.0899 0.1085 0.6238 0.5981
A-375 Vemurafenib Defactinib 0.100 3.160
uM
 72
hr
 2 2204 325 0.0900 0.0825 0.1475 0.1694
MZ7-mel Vemurafenib Dasatinib 3.160 3.160
uM
 72
hr
 3 536 86 0.0905 0.1047 0.1604 0.1707
A-375 Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 3 1827 89 0.0910 0.1035 0.0487 0.0423
A-375 Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 1 2098 334 0.0923 0.0842 0.1592 0.1524
COLO 858 Vemurafenib Belinostat 1.000 1.000
uM
 72
hr
 2 1194 791 0.0925 0.0829 0.6625 0.6809
A-375 Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 2 2198 268 0.0925 0.0889 0.1219 0.1262
COLO 858 Vemurafenib I-BET 1.000 1.000
uM
 72
hr
 2 1193 888 0.0932 0.0928 0.7443 0.7455
COLO 858 Vemurafenib Belinostat 3.160 1.000
uM
 72
hr
 1 1468 1062 0.0932 0.0767 0.7234 0.7291
A-375 Vemurafenib Defactinib 3.160 1.000
uM
 72
hr
 1 2292 344 0.0934 0.0857 0.1501 0.1490
COLO 858 Vemurafenib JNK-IN-8 0.316 3.160
uM
 72
hr
 1 1246 683 0.0934 0.0962 0.5482 0.5276
COLO 858 Vemurafenib I-BET 3.160 1.000
uM
 72
hr
 1 1635 1328 0.0939 0.0728 0.8122 0.8214
A-375 Vemurafenib Defactinib 1.000 1.000
uM
 72
hr
 3 2145 178 0.0943 0.1060 0.0830 0.0803
COLO 858 Vemurafenib JNK-IN-8 0.316 3.160
uM
 72
hr
 2 1207 631 0.0955 0.0962 0.5228 0.5276
COLO 858 Vemurafenib Defactinib 0.316 1.000
uM
 72
hr
 3 1514 710 0.0955 0.1083 0.4690 0.4526
A-375 Vemurafenib Belinostat 0.100 1.000
uM
 72
hr
 1 1844 583 0.0963 0.0930 0.3162 0.3181
A-375 Vemurafenib JNK-IN-8 1.000 3.160
uM
 72
hr
 1 1798 263 0.0966 0.0897 0.1463 0.1612
COLO 858 Vemurafenib I-BET151 3.160 1.000
uM
 72
hr
 1 1460 1042 0.0966 0.0871 0.7137 0.7176
MZ7-mel Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 3 475 178 0.0969 0.1000 0.3747 0.3467
A-375 Vemurafenib Belinostat 0.100 1.000
uM
 72
hr
 2 1843 570 0.0972 0.0930 0.3093 0.3181
COLO 858 Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 2 1185 610 0.0974 0.1170 0.5148 0.4614