Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| COLO 858 | Vemurafenib | Dasatinib | 3.160 | 0.000 | uM | 72 | hr | 3 | 1681 | 1503 | 0.0254 | 0.0314 | 0.8941 | 0.8595 |
| A-375 | Vemurafenib | I-BET151 | 0.000 | 0.000 | uM | 72 | hr | 3 | 13787 | 1514 | 0.8871 | 1.0000 | 0.1098 | 0.1052 |
| COLO 858 | Vemurafenib | Defactinib | 3.160 | 0.000 | uM | 72 | hr | 1 | 1712 | 1553 | 0.0189 | 0.0193 | 0.9071 | 0.9069 |
| COLO 858 | Vemurafenib | Defactinib | 3.160 | 0.000 | uM | 72 | hr | 2 | 1727 | 1557 | 0.0202 | 0.0193 | 0.9016 | 0.9069 |
| A-375 | Vemurafenib | I-BET151 | 0.000 | 0.000 | uM | 72 | hr | 2 | 15439 | 1571 | 1.0024 | 1.0000 | 0.1018 | 0.1052 |
| A-375 | Vemurafenib | I-BET | 0.000 | 0.000 | uM | 72 | hr | 2 | 14872 | 1575 | 0.9751 | 1.0000 | 0.1059 | 0.1030 |
| A-375 | Vemurafenib | I-BET | 0.000 | 0.000 | uM | 72 | hr | 1 | 16558 | 1621 | 1.0954 | 1.0000 | 0.0979 | 0.1030 |
| COLO 858 | Vemurafenib | Defactinib | 0.000 | 0.316 | uM | 72 | hr | 3 | 9755 | 1627 | 0.9650 | 0.8985 | 0.1668 | 0.1651 |
| COLO 858 | Vemurafenib | Defactinib | 3.160 | 0.000 | uM | 72 | hr | 3 | 1810 | 1651 | 0.0189 | 0.0193 | 0.9122 | 0.9069 |
| A-375 | Vemurafenib | I-BET151 | 0.000 | 0.000 | uM | 72 | hr | 1 | 17149 | 1786 | 1.1105 | 1.0000 | 0.1041 | 0.1052 |