Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib Defactinib 1.000 0.316
uM
 72
hr
 3 1675 1292 0.0455 0.0451 0.7713 0.7585
COLO 858 Vemurafenib I-BET 3.160 1.000
uM
 72
hr
 1 1635 1328 0.0939 0.0728 0.8122 0.8214
COLO 858 Vemurafenib (+)-JQ1 1.000 1.000
uM
 72
hr
 1 1542 1339 0.0616 0.0535 0.8684 0.8621
A-375 Vemurafenib Belinostat 0.000 0.000
uM
 72
hr
 1 13881 1351 0.9567 1.0000 0.0973 0.0803
COLO 858 Vemurafenib (+)-JQ1 3.160 1.000
uM
 72
hr
 1 1645 1369 0.0838 0.0609 0.8322 0.8549
COLO 858 Vemurafenib Dasatinib 3.160 1.000
uM
 72
hr
 1 1440 1382 0.0083 0.0084 0.9597 0.9531
COLO 858 Vemurafenib Defactinib 3.160 1.000
uM
 72
hr
 2 1444 1385 0.0070 0.0077 0.9591 0.9513
COLO 858 Vemurafenib Dasatinib 3.160 0.000
uM
 72
hr
 2 1560 1386 0.0249 0.0314 0.8885 0.8595
COLO 858 Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 2 8670 1397 0.8635 0.8985 0.1611 0.1651
COLO 858 Vemurafenib Belinostat 3.160 0.000
uM
 72
hr
 3 1747 1411 0.0771 0.0685 0.8077 0.8137
COLO 858 Vemurafenib Defactinib 3.160 0.316
uM
 72
hr
 3 1488 1416 0.0085 0.0082 0.9516 0.9545
COLO 858 Vemurafenib Defactinib 3.160 0.316
uM
 72
hr
 2 1479 1417 0.0074 0.0082 0.9581 0.9545
A-375 Vemurafenib Belinostat 0.000 0.000
uM
 72
hr
 2 14602 1419 1.0065 1.0000 0.0972 0.0803
A-375 Vemurafenib (+)-JQ1 0.000 0.000
uM
 72
hr
 3 14150 1426 0.8998 1.0000 0.1008 0.0814
COLO 858 Vemurafenib JNK-IN-8 3.160 1.000
uM
 72
hr
 1 1553 1428 0.0207 0.0156 0.9195 0.9257
COLO 858 Vemurafenib Defactinib 3.160 1.000
uM
 72
hr
 1 1509 1433 0.0090 0.0077 0.9496 0.9513
COLO 858 Vemurafenib Belinostat 3.160 0.000
uM
 72
hr
 2 1761 1456 0.0700 0.0685 0.8268 0.8137
COLO 858 Vemurafenib Defactinib 0.000 0.000
uM
 72
hr
 1 10128 1461 1.0290 1.0000 0.1443 0.1501
COLO 858 Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 1 8772 1469 0.8671 0.8985 0.1675 0.1651
COLO 858 Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 1 1539 1471 0.0115 0.0099 0.9558 0.9514
COLO 858 Vemurafenib Defactinib 3.160 0.316
uM
 72
hr
 1 1556 1484 0.0085 0.0082 0.9537 0.9545
A-375 Vemurafenib (+)-JQ1 0.000 0.000
uM
 72
hr
 2 14840 1490 0.9441 1.0000 0.1004 0.0814
A-375 Vemurafenib I-BET 0.000 0.000
uM
 72
hr
 3 14167 1492 0.9295 1.0000 0.1053 0.1030
COLO 858 Vemurafenib Defactinib 0.000 0.000
uM
 72
hr
 3 9513 1495 0.9520 1.0000 0.1572 0.1501
COLO 858 Vemurafenib Defactinib 0.000 0.000
uM
 72
hr
 2 10083 1500 1.0190 1.0000 0.1488 0.1501