Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
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MMAC-SF | Vemurafenib | JNK-IN-8 | 0.000 | 0.316 | uM | 72 | hr | 2 | 1516 | 54 | 1.4357 | 1.3028 | 0.0356 | 0.0415 |
MZ7-mel | Vemurafenib | PF562271 | 0.000 | 0.316 | uM | 72 | hr | 1 | 4085 | 262 | 1.1029 | 1.3927 | 0.0641 | 0.0616 |
MZ7-mel | Vemurafenib | PF562271 | 0.000 | 0.316 | uM | 72 | hr | 2 | 5640 | 348 | 1.5267 | 1.3927 | 0.0617 | 0.0616 |
MZ7-mel | Vemurafenib | PF562271 | 0.000 | 0.316 | uM | 72 | hr | 3 | 5704 | 336 | 1.5486 | 1.3927 | 0.0589 | 0.0616 |
MZ7-mel | Vemurafenib | Saracatinib | 0.000 | 0.316 | uM | 72 | hr | 2 | 4806 | 288 | 1.4736 | 1.4168 | 0.0599 | 0.0618 |
MZ7-mel | Vemurafenib | Saracatinib | 0.000 | 0.316 | uM | 72 | hr | 3 | 6287 | 334 | 1.9416 | 1.4168 | 0.0531 | 0.0618 |
MZ7-mel | Vemurafenib | Saracatinib | 0.000 | 0.316 | uM | 72 | hr | 1 | 2761 | 200 | 0.8353 | 1.4168 | 0.0724 | 0.0618 |
MZ7-mel | Vemurafenib | JNK-IN-8 | 0.000 | 0.316 | uM | 72 | hr | 2 | 5203 | 279 | 1.5612 | 1.5833 | 0.0536 | 0.0617 |
MZ7-mel | Vemurafenib | JNK-IN-8 | 0.000 | 0.316 | uM | 72 | hr | 3 | 7109 | 392 | 2.1297 | 1.5833 | 0.0551 | 0.0617 |
MZ7-mel | Vemurafenib | JNK-IN-8 | 0.000 | 0.316 | uM | 72 | hr | 1 | 3616 | 276 | 1.0590 | 1.5833 | 0.0763 | 0.0617 |