Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib Defactinib 3.160 3.160
uM
 72
hr
 1 921 884 0.0044 0.0047 0.9598 0.9535
COLO 858 Vemurafenib Defactinib 3.160 0.316
uM
 72
hr
 3 1488 1416 0.0085 0.0082 0.9516 0.9545
COLO 858 Vemurafenib Defactinib 3.160 0.316
uM
 72
hr
 2 1479 1417 0.0074 0.0082 0.9581 0.9545
COLO 858 Vemurafenib Defactinib 3.160 0.316
uM
 72
hr
 1 1556 1484 0.0085 0.0082 0.9537 0.9545
COLO 858 Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 1 661 623 0.0064 0.0054 0.9425 0.9547
COLO 858 Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 3 752 724 0.0047 0.0054 0.9628 0.9547
COLO 858 Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 2 726 696 0.0051 0.0054 0.9587 0.9547
COLO 858 Vemurafenib Dasatinib 3.160 0.316
uM
 72
hr
 2 937 901 0.0051 0.0064 0.9616 0.9579
COLO 858 Vemurafenib Dasatinib 3.160 0.316
uM
 72
hr
 1 1135 1078 0.0081 0.0064 0.9498 0.9579
COLO 858 Vemurafenib Dasatinib 3.160 0.316
uM
 72
hr
 3 1090 1049 0.0059 0.0064 0.9624 0.9579