Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib Belinostat 3.160 0.000
uM
 72
hr
 3 1747 1411 0.0771 0.0685 0.8077 0.8137
COLO 858 Vemurafenib Belinostat 3.160 1.000
uM
 72
hr
 1 1468 1062 0.0932 0.0767 0.7234 0.7291
COLO 858 Vemurafenib Belinostat 3.160 1.000
uM
 72
hr
 2 1263 917 0.0794 0.0767 0.7260 0.7291
COLO 858 Vemurafenib Belinostat 3.160 1.000
uM
 72
hr
 3 957 706 0.0576 0.0767 0.7377 0.7291
MMAC-SF Vemurafenib JNK-IN-8 3.160 0.000
uM
 72
hr
 1 504 169 0.3290 0.3466 0.3353 0.3504
MMAC-SF Vemurafenib JNK-IN-8 3.160 0.000
uM
 72
hr
 2 492 180 0.3064 0.3466 0.3659 0.3504
MMAC-SF Vemurafenib JNK-IN-8 3.160 0.000
uM
 72
hr
 3 634 222 0.4046 0.3466 0.3502 0.3504
MMAC-SF Vemurafenib JNK-IN-8 3.160 0.316
uM
 72
hr
 1 337 88 0.2445 0.2619 0.2611 0.2293
MMAC-SF Vemurafenib JNK-IN-8 3.160 0.316
uM
 72
hr
 2 296 50 0.2416 0.2619 0.1689 0.2293
MMAC-SF Vemurafenib JNK-IN-8 3.160 0.316
uM
 72
hr
 3 411 106 0.2995 0.2619 0.2579 0.2293