Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WM-115 | Vemurafenib | Defactinib | 0.000 | 1.000 | uM | 72 | hr | 3 | 2973 | 240 | 0.6533 | 0.6669 | 0.0807 | 0.0743 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 1.000 | uM | 72 | hr | 2 | 2853 | 215 | 0.6305 | 0.6669 | 0.0754 | 0.0743 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 1.000 | uM | 72 | hr | 1 | 3214 | 215 | 0.7168 | 0.6669 | 0.0669 | 0.0743 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 0.316 | uM | 72 | hr | 3 | 3709 | 210 | 0.8363 | 0.8635 | 0.0566 | 0.0685 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 0.316 | uM | 72 | hr | 2 | 4089 | 304 | 0.9047 | 0.8635 | 0.0743 | 0.0685 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 0.316 | uM | 72 | hr | 1 | 3840 | 286 | 0.8495 | 0.8635 | 0.0745 | 0.0685 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 0.000 | uM | 72 | hr | 3 | 4497 | 283 | 1.0073 | 1.0000 | 0.0629 | 0.0611 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 0.000 | uM | 72 | hr | 2 | 4436 | 277 | 0.9941 | 1.0000 | 0.0624 | 0.0611 |
| WM-115 | Vemurafenib | Defactinib | 0.000 | 0.000 | uM | 72 | hr | 1 | 4435 | 257 | 0.9986 | 1.0000 | 0.0579 | 0.0611 |
| WM-115 | Vemurafenib | Dasatinib | 3.160 | 3.160 | uM | 72 | hr | 3 | 941 | 527 | 0.1033 | 0.1103 | 0.5600 | 0.5337 |