Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 1 2110 115 0.4012 0.3143 0.0545 0.0600
A-375 Vemurafenib Defactinib 0.100 0.000
uM
 72
hr
 1 13441 248 0.6323 0.4565 0.0185 0.0200
WM-115 Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 1 1897 677 0.3045 0.2911 0.3569 0.3460
MZ7-mel Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 1 1692 86 0.3230 0.2758 0.0508 0.0483
A-375 Vemurafenib PF562271 0.316 1.000
uM
 72
hr
 1 2803 103 0.1469 0.1343 0.0367 0.0352
WM-115 Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 1 1897 707 0.2971 0.2711 0.3727 0.3806
MZ7-mel Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 1 1700 292 0.2831 0.3589 0.1718 0.1593
COLO 858 Vemurafenib Belinostat 0.000 1.000
uM
 72
hr
 1 952 361 0.1356 0.1295 0.3792 0.3690
WM-115 Vemurafenib Dasatinib 0.316 0.000
uM
 72
hr
 1 3002 210 0.6970 0.7092 0.0700 0.0818
MZ7-mel Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 1 1165 126 0.2089 0.2583 0.1082 0.1001