Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Dasatinib 0.100 1.000
uM
 72
hr
 3 653 30 0.4772 0.6038 0.0459 0.0460
MMAC-SF Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 2 837 30 0.4972 0.4909 0.0358 0.0363
MMAC-SF Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 3 622 28 0.5833 0.6789 0.0450 0.0471
MMAC-SF Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 2 619 26 0.6004 0.6021 0.0420 0.0426
MMAC-SF Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 3 548 26 0.5126 0.6959 0.0474 0.0496
MMAC-SF Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 3 694 22 0.5362 0.6941 0.0317 0.0337
MMAC-SF Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 3 617 21 0.3672 0.4909 0.0340 0.0363
MMAC-SF Vemurafenib PF562271 0.000 3.160
uM
 72
hr
 3 451 21 0.4354 0.6021 0.0466 0.0426
MMAC-SF Vemurafenib PF562271 0.000 1.000
uM
 72
hr
 3 562 20 0.5488 0.6166 0.0356 0.0527
MMAC-SF Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 3 673 16 0.5242 0.6896 0.0238 0.0319