Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
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COLO 858 | Vemurafenib | PF562271 | 1.000 | 3.160 | uM | 72 | hr | 3 | 477 | 452 | 0.0045 | 0.0058 | 0.9476 | 0.9416 |
COLO 858 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 3 | 752 | 724 | 0.0047 | 0.0054 | 0.9628 | 0.9547 |
COLO 858 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 2 | 726 | 696 | 0.0051 | 0.0054 | 0.9587 | 0.9547 |
COLO 858 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 1 | 661 | 623 | 0.0064 | 0.0054 | 0.9425 | 0.9547 |
COLO 858 | Vemurafenib | Defactinib | 3.160 | 3.160 | uM | 72 | hr | 1 | 921 | 884 | 0.0044 | 0.0047 | 0.9598 | 0.9535 |
COLO 858 | Vemurafenib | Defactinib | 3.160 | 3.160 | uM | 72 | hr | 2 | 809 | 781 | 0.0033 | 0.0047 | 0.9654 | 0.9535 |
COLO 858 | Vemurafenib | Defactinib | 3.160 | 3.160 | uM | 72 | hr | 3 | 850 | 795 | 0.0065 | 0.0047 | 0.9353 | 0.9535 |
COLO 858 | Vemurafenib | PF562271 | 3.160 | 3.160 | uM | 72 | hr | 2 | 424 | 402 | 0.0040 | 0.0041 | 0.9481 | 0.9488 |
COLO 858 | Vemurafenib | PF562271 | 3.160 | 3.160 | uM | 72 | hr | 1 | 486 | 455 | 0.0056 | 0.0041 | 0.9362 | 0.9488 |
COLO 858 | Vemurafenib | PF562271 | 3.160 | 3.160 | uM | 72 | hr | 3 | 422 | 406 | 0.0029 | 0.0041 | 0.9621 | 0.9488 |