Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
A-375 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 1 3954 69 0.2034 0.1687 0.0175 0.0176
A-375 Vemurafenib Defactinib 0.100 0.316
uM
 72
hr
 3 6615 115 0.3115 0.3141 0.0174 0.0173
A-375 Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 2 6975 120 0.3729 0.3515 0.0172 0.0163
A-375 Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 1 6033 99 0.3228 0.3515 0.0164 0.0163
A-375 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 2 7416 121 0.4589 0.4477 0.0163 0.0178
A-375 Vemurafenib Defactinib 0.100 0.316
uM
 72
hr
 2 6957 110 0.3281 0.3141 0.0158 0.0173
A-375 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 2 3199 50 0.1648 0.1687 0.0156 0.0176
A-375 Vemurafenib PF562271 0.100 0.316
uM
 72
hr
 3 6696 102 0.3587 0.3515 0.0152 0.0163
A-375 Vemurafenib Belinostat 0.100 0.000
uM
 72
hr
 3 6342 95 0.4770 0.4690 0.0150 0.0238
A-375 Vemurafenib Dasatinib 0.100 0.000
uM
 72
hr
 1 7790 111 0.3888 0.4180 0.0142 0.0173